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218600-44-3 Basic information More..
Product Name:Bardoxolone
Synonyms:2-Cyano-3,12-dioxooleana-1,9-dien-28-oic acid;CDDO(Bardoxolone);BARDOXOLONE;CDDO;RTA 401;Oleana-1,9(11)-dien-28-oic acid, 2-cyano-3,12-dioxo-;Bardoxolone;CDDO;RTA 401;2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid
CAS:218600-44-3
MF:C31H41NO4
MW:491.66
EINECS:
Mol File:218600-44-3.mol
218600-44-3

Use

Bardoxolone is a synthetic oleanane triterpenoid that exerts multifunctional activities in the control of cellular growth and differentiation. Bardoxolone is capable of activating the transcription fa ctor peroxisome proliferator activator receptor-γ (PPARγ), its apoptotic effects in malignant cells have been shown to occur independently of PPARγ. Bardoxolone was developed as an potential drug for the improvement of hyperglycemia, proteinuria, glomerulus structure, serum creatine, which may in turn be beneficial to treat diabetic kidney diseases, cancer and thromboembolic events.

Bardoxolone manufacturers

  • Bardoxolone
  • US $68.00-112.00 / mg
  • 2025-04-30
  • CAS:218600-44-3
  • Min. Order:
  • Purity: 97.9%
  • Supply Ability: 10g
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