| 202475-60-3 Basic information More.. |
Product Name: | JAK3 INHIBITOR I | Synonyms: | 4-(4'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE;JAK3 INHIBITOR I;WHI-P131;Janex 1;A JAK3 inhibitor
WHI-P131;4-(6,7-dimethoxyquinazolin-4-ylamino)phenol;WHI-P131(Janex 1);JANEX-1;WHI-P131 | CAS: | 202475-60-3 | MF: | C16H15N3O3 | MW: | 297.31 | EINECS: | | Mol File: | 202475-60-3.mol | |
Use
Janex 1 is a Janus tyrosine kinase 3 (JAK3) inhibitor. Inhibition of JAK3 has been shown to exhibit protective action against the development of T1D in non-obese diabetic (NOD) mice. Janex 1 has been shown to suppresses proliferation of short-term cultured NOD CD4+ T cells through induction of apoptosis, while promoting survival of a particular population of long-term cultured cells. It ameliorates the expression of TNF-α-induced cell adhesion molecules and improves myocardial vascular permeability.
- JANEX-1
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- US $37.00-84.00 / mg
- 2024-11-14
- CAS:202475-60-3
- Min. Order:
- Purity: 99.73%
- Supply Ability: 10g
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202475-60-3
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