| | 3562-63-8 Basic information More.. |
| Product Name: | Megestrol | | Synonyms: | 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione;20-dione,17-hydroxy-6-methyl-pregna-6-diene-3;4,6-PREGNADIEN-6-METHYL-17-OL-3,20-DIONE;17-ALPHA-HYDROXY-6-METHYL-4,6-PREGNADIENE-3,20-DIONE;MEGESTROL;17-alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione;Megestrol (base and/or unspecified salts);C07120 | | CAS: | 3562-63-8 | | MF: | C22H30O3 | | MW: | 342.47 | | EINECS: | 222-628-6 | | Mol File: | 3562-63-8.mol |  |
Use
Megestrol acetate, a synthetic progestogen, was introduced in the
early 1960s as a component in oral contraceptive preparations. In 1967, as a result
of new regulations required by the United States Food and Drug Administration,
megestrol acetate was submitted to long-term toxicity studies and by the early
1970s it was shown to be associated with an increased incidence of mammary
tumours in beagle bitches which led to its withdrawal by several regulatory
authorities. Subsequently the validity of the beagle bitch model as a predictor of
carcinogenicity of steroid contraceptives has been contested by many national
regulatory authorities and megestrol remains available in some countries for
contraceptive purposes. In other countries its use is restricted to anticancer
treatment.
(Reference: (WHODI) WHO Drug Information, 1-3, 5-7, 1984)
- Megestrol
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- US $0.00-0.00 / KG
- 2025-04-25
- CAS:3562-63-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20
- Megestrol
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- US $0.00 / KG
- 2025-04-24
- CAS:3562-63-8
- Min. Order: 1KG
- Purity: 0.99
- Supply Ability: 1000KG
- Megestrol
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- US $1.10 / g
- 2025-04-17
- CAS:3562-63-8
- Min. Order: 1g
- Purity: 99.0% min
- Supply Ability: 100 tons min
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3562-63-8
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