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950762-95-5 Basic information More..
Product Name:PCI 34051
Synonyms:N-hydroxy-1-(4-Methoxybenzyl)-1H-indole-6-carboxaMide;PCI 34051;PCI-34051;1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide;1H-Indole-6-carboxamide, N-hydroxy-1-[(4-methoxyphenyl)methyl]-;N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide;PCI-34051;PCI 34051;N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
CAS:950762-95-5
MF:C17H16N2O3
MW:296.32
EINECS:
Mol File:950762-95-5.mol
950762-95-5

Use

PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast.

PCI 34051 manufacturers

  • PCI-34051
  • US $55.00-195.00 / mg
  • 2024-11-07
  • CAS:950762-95-5
  • Min. Order:
  • Purity: 99.14%
  • Supply Ability: 10g
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