| | 125-65-5 Basic information More.. |
| Product Name: | Pleuromulin | | Synonyms: | PLEUROMULIN;PLEUROMUTILIN;a4014c;antibioticbc757;bc757;drosopholinb;glycolicacid,8-esterwithoctahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-6-viny;l-3a,9-propano-3ah-cyclopentacycloocten-1(4h)-one | | CAS: | 125-65-5 | | MF: | C22H34O5 | | MW: | 378.5 | | EINECS: | 204-747-5 | | Mol File: | 125-65-5.mol |  |
Use
Pleuromulin is Crystalline Solid
Pleuromutilin is a diterpene produced by several species of basidomycete, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Pleuromutilin inhibits protein synthesis by binding to domain V of 23S rRNA and this has led to the development of many semi-synthetic analogues as new generation antibiotics, such as tiamulin and retapamulin.
Pleuromutilins such as tiamulin and valnemulin have been used for some time in veterinary medicine to treat swine infections. More recently a semisynthetic pleuromutilin, retapamulin, has been introduced as a topical treatment for Gram-positive infections in humans. Pleuromutilins inhibit the peptidyl transferase activity of the bacterial 50S ribosomal subunit by binding to the A site.
- Pleuromulin
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- US $30.00 / kg
- 2025-04-15
- CAS:125-65-5
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 100 tons
- Pleuromulin
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- US $10.00 / KG
- 2025-03-31
- CAS:125-65-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- antibioticbc757
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- US $0.00 / KG
- 2025-03-21
- CAS:125-65-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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125-65-5
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