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210421-74-2 Basic information More..
Product Name:Sitaxentan sodium
Synonyms:Sodium (4-chloro-3-methyl-1,2-oxazol-5-yl)-[2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]thiophen-3-yl]sulfonylazanide;SITAXSENTAN SODIUM;TBC-11249;Thelin;sitaxentan sodiuM;N-(4-Chloro-3-Methylisoxazol-5-yl)-2-[2-(6-Methyl-1,3-Benzodioxol-5-yl)acetyl]thiophene-3-sulfonaMide;N-(4-Chloro-3-Methyl-5-isoxazolyl)-2-[2-(6-Methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonaMide;TBC11251 sodiuM salt
CAS:210421-74-2
MF:C18H14ClN2NaO6S2
MW:476.89
EINECS:
Mol File:210421-74-2.mol
210421-74-2

Use

Sitaxentan sodium, belongs to thesulfonamide class of endothelin receptor antagonists.Although it has 6,000-fold selectivity for the ETA receptor,clinical trials have not demonstrated a greater efficacyover bosentan. However, it has much lower liver toxicitythan bosentan. The manufacturer is attempting to meetefficacy outcomes set by the FDA, which must be met beforeapproval of sitaxsentan as a therapeutic agent will begranted.

Sitaxentan sodium manufacturers

  • Sitaxsentan sodium
  • US $30.00-103.00 / mg
  • 2024-11-19
  • CAS:210421-74-2
  • Min. Order:
  • Purity: ≥95%
  • Supply Ability: 10g
  • Sitaxentan sodium
  • US $2.00 / kg
  • 2019-07-06
  • CAS:210421-74-2
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100kg
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