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10048-13-2 Basic information More..
Product Name:STERIGMATOCYSTIN
Synonyms:SterigMatocystin froM Aspergillus Versicolor;NSC 201423 NSC 204985 Sterigmatocystin;(3aR,12cS)-3a,12c-Dihydro-8-hydroxy-6-Methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one;NSC 201423;NSC 204985;(3aR,12cS)-8-hydroxy-6-methoxy-3aH-furo[3',2':4,5]furo[2,3-c]xanthen-7(12cH)-one;STERIGMATOCYSTIN;STERIGMATOCYSTIN, ASPERGILLUS VERSICOLOR
CAS:10048-13-2
MF:C18H12O6
MW:324.28
EINECS:233-158-6
Mol File:10048-13-2.mol
10048-13-2

Use

Sterigmatocystin is a xanthone produced by several species of Aspergillus, isolated by a number of research groups in the 1950s as a mycotoxin associated with food and grain contamination. Sterigmatocystin is structurally related to the aflatoxins and, while it is considered to be mutagenic, teratogenic and carcinogenic, it is less widespread and potent than the aflatoxins. Sterigmatocystin, in the presence of microsomes, covalently binds to DNA. It uncouples oxidative phosphorylation but, unlike the aflatoxins, does not induce mitochondrial swelling or hinder Ca2+-induced swelling of mitochondria. Sterigmatocystin also inhibits acyl-CoA:cholesterol acyltransferase (ACAT) with selectivity for the ACAT2 isoenzyme.

STERIGMATOCYSTIN manufacturers

  • Sterigmatocystine
  • US $364.00-0.00 / mg
  • 2024-10-24
  • CAS:10048-13-2
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  • Supply Ability: 10g
  • STERIGMATOCYSTIN
  • US $1.00 / g
  • 2019-12-23
  • CAS:10048-13-2
  • Min. Order: 100g
  • Purity: 99%
  • Supply Ability: G/KG/T
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