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ChemicalBook >> CAS DataBase List >> lenvatinib Mesylate

lenvatinib Mesylate

lenvatinib Mesylate price.
  • $29 - $800
  • Product name: lenvatinib Mesylate
  • CAS: 857890-39-2
  • MF: C22H23ClN4O7S
  • MW: 522.95862
  • EINECS:812-398-0
  • MDL Number:MFCD18633219
  • Synonyms:lenvatinib Methanesulfonate;E7080 Mesylate;4-[3chloro-4-(N'-cyclopropylureido)phenoxy]-7-methoxyquinoline-6-carboxamide methanesulfonate;lenvatinib Mesylate;CAT#A863437;Lenvatinib Mesylate,Amadis Chemical offer CAS#857890-39-2;E7080;E-7080;E 7080;maltitol E:candyli(at)speedgainpharma(dot)com
22 prices
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  • AK Scientific
  • American Custom Chemicals Corporation
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • ManufacturerAK Scientific
  • Product number0004AP
  • Product descriptionLenvatinibMesilate
  • Packaging250mg
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001517
  • Product descriptionE-7080 METHYLSULFONATE 95.00%
  • Packaging5MG
  • Price$505.41
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3379
  • Product descriptionLenvatinib Mesylate
  • Packaging5mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3379
  • Product descriptionLenvatinib Mesylate
  • Packaging25mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3379
  • Product descriptionLenvatinib Mesylate
  • Packaging100mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3379
  • Product descriptionLenvatinib Mesylate
  • Packaging1g
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3379
  • Product descriptionLenvatinib Mesylate
  • Packaging10g
  • Price$749
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL166696
  • Product descriptionLenvatinib mesylate
  • Packaging10mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL166696
  • Product descriptionLenvatinib mesylate
  • Packaging50mg
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29832
  • Product descriptionLenvatinib (mesylate)
  • Packaging500mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29832
  • Product descriptionLenvatinib (mesylate)
  • Packaging1g
  • Price$135
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29832
  • Product descriptionLenvatinib (mesylate)
  • Packaging5g
  • Price$421
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM144679
  • Product description4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamidemethanesulfonate 97%
  • Packaging1g
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM144679
  • Product description4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamidemethanesulfonate 97%
  • Packaging5g
  • Price$421
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0030963
  • Product descriptionLenvatinib(mesylate) 98.54%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0030963
  • Product descriptionLenvatinib(mesylate) 98.54%
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0004AP LenvatinibMesilate 250mg $131 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001517 E-7080 METHYLSULFONATE 95.00% 5MG $505.41 2021-12-16 Buy
AvaChem 3379 Lenvatinib Mesylate 5mg $29 2021-12-16 Buy
AvaChem 3379 Lenvatinib Mesylate 25mg $49 2021-12-16 Buy
AvaChem 3379 Lenvatinib Mesylate 100mg $79 2021-12-16 Buy
AvaChem 3379 Lenvatinib Mesylate 1g $149 2021-12-16 Buy
AvaChem 3379 Lenvatinib Mesylate 10g $749 2021-12-16 Buy
Biosynth Carbosynth BL166696 Lenvatinib mesylate 10mg $76 2021-12-16 Buy
Biosynth Carbosynth BL166696 Lenvatinib mesylate 50mg $162 2021-12-16 Buy
Cayman Chemical 29832 Lenvatinib (mesylate) 500mg $86 2024-03-01 Buy
Cayman Chemical 29832 Lenvatinib (mesylate) 1g $135 2024-03-01 Buy
Cayman Chemical 29832 Lenvatinib (mesylate) 5g $421 2024-03-01 Buy
Chemenu CM144679 4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamidemethanesulfonate 97% 1g $153 2021-12-16 Buy
Chemenu CM144679 4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamidemethanesulfonate 97% 5g $421 2021-12-16 Buy
ChemScene CS-0030963 Lenvatinib(mesylate) 98.54% 10mg $70 2021-12-16 Buy
ChemScene CS-0030963 Lenvatinib(mesylate) 98.54% 50mg $150 2021-12-16 Buy

Properties

Melting point :>220°C (dec.)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
InChIKey :HWLFIUUAYLEFCT-UHFFFAOYSA-N
SMILES :O=C(N)C1C=C2C(N=CC=C2OC2C=C(Cl)C(NC(=O)NC3CC3)=CC=2)=CC=1OC.CS(=O)(O)=O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lenvatinib mesylate (lenvatinib) is an oral targeted therapy medicine known as a receptor‐type tyrosine kinase inhibitor. It is a small-molecule drug (a drug that can enter cells easily), which was developed at Eisai in 2015. It was approved by the FDA in 2015 for the treatment of differentiated thyroid cancer that is either locally recurrent, metastatic, or progressive and did not respond to radioactive iodine treatment. In May 2016, the FDA approved the drug as a combination therapy with everolimus for the treatment of advanced renal cell carcinoma. Because VEGF (and fibroblast growth factor receptors, known as FGFRs) are thought to play a role in cardiovascular signaling pathways, VEGF2R and FGFR inhibition are thought to be the mechanisms behind the primary side effect of lenvatinib mesylate, which is hypertension.

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