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ChemicalBook >> CAS DataBase List >> a-Hydroxy Tamoxifen

a-Hydroxy Tamoxifen

a-Hydroxy Tamoxifen price.
  • $32 - $1880
  • Product name: a-Hydroxy Tamoxifen
  • CAS: 97151-02-5
  • MF: C26H29NO2
  • MW: 387.52
  • EINECS:
  • MDL Number:MFCD02101152
  • Synonyms:(E)-α-Hydroxy Tamoxifen;(E)-(+/-)-alpha-Hydroxytamoxifen;α-OHTAM;Benzeneethanol, β-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methyl-, (βE)-;α-hydroxy Tamoxifen;(E)-α-Hydroxy tamoxifen;α-OHTAM;Benzeneethanol,b-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-a-methyl-,(bE)-
7 prices
Selected condition：
Brand
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • TRC
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerCayman Chemical
  • Product number17204
  • Product descriptionα-hydroxy Tamoxifen ≥98%
  • Packaging500μg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17204
  • Product descriptionα-hydroxy Tamoxifen ≥98%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17204
  • Product descriptionα-hydroxy Tamoxifen ≥98%
  • Packaging5mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17204
  • Product descriptionα-hydroxy Tamoxifen ≥98%
  • Packaging10mg
  • Price$335
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number11033
  • Product descriptionα-HydroxyTamoxifen
  • Packaging50mg
  • Price$1880
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberH954700
  • Product description(E)-α-HydroxyTamoxifen
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberH954700
  • Product description(E)-α-HydroxyTamoxifen
  • Packaging10mg
  • Price$145
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 17204 α-hydroxy Tamoxifen ≥98% 500μg $32 2024-03-01 Buy
Cayman Chemical 17204 α-hydroxy Tamoxifen ≥98% 1mg $57 2024-03-01 Buy
Cayman Chemical 17204 α-hydroxy Tamoxifen ≥98% 5mg $214 2024-03-01 Buy
Cayman Chemical 17204 α-hydroxy Tamoxifen ≥98% 10mg $335 2024-03-01 Buy
Medical Isotopes, Inc. 11033 α-HydroxyTamoxifen 50mg $1880 2021-12-16 Buy
TRC H954700 (E)-α-HydroxyTamoxifen 1mg $45 2021-12-16 Buy
TRC H954700 (E)-α-HydroxyTamoxifen 10mg $145 2021-12-16 Buy

Properties

Melting point :115-119°C
Boiling point :533.8±50.0 °C(Predicted)
Density :1.094±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :14.13±0.20(Predicted)
form :Solid
color :Pale Yellow to Pale Beige

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Tamoxifen is a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. Although it is an antagonist of ER action in breast tissue, it acts as an ER agonist in bone and blood vessels and a partial ER agonist in uterine tissues. α-hydroxy Tamoxifen is a reactive metabolite of tamoxifen that is formed by the action of cytochrome P450 3A4 in human liver. It can be further converted into genotoxic DNA adducts though a mechanism involving reversible O-sulfonation of the hydroxyl moiety, which in rats has been linked with hepatocarcinoma.

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