ZEBULARINE
|
- $8 - $1200
- Product name: ZEBULARINE
- CAS: 3690-10-6
- MF: C9H12N2O5
- MW: 228.2
- EINECS:2017-001-1
- MDL Number:MFCD04973699
- Synonyms:4-Deoyuridine;1-b-D-ribofuranosyl-2-(1H)-pyriMidinone;anticancer drug, DNA Methylation inhibitor;2(1H)-Pyrimidinone, 1-β-D-ribofuranosyl-;2-Pyrimidone-1-β-D-riboside;1-beta-D-Ribofuranosyl-2(1H)-pyrimidinone;Pyrimidin-2-one beta-D-ribofuranoside;1-(β-d-ribofuranosyl)-1,2-dihydropyrimidin-2-one
39 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Arctom
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 10mM(in 1mL DMSO)
- 50mg
- 100mg
- 200MG
- 250mg
- 500mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product number2817AH
- Product descriptionZebularine
- Packaging250mg
- Price$228
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1915
- Product descriptionZebularine
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1915
- Product descriptionZebularine
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1915
- Product descriptionZebularine
- Packaging50mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIA8416
- Product descriptionZebularine
- Packaging50mg
- Price$203
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIA8416
- Product descriptionZebularine
- Packaging100mg
- Price$319
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS459323
- Product descriptionZebularine ≥98%
- Packaging5mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS459323
- Product descriptionZebularine ≥98%
- Packaging10mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS459323
- Product descriptionZebularine ≥98%
- Packaging50mg
- Price$17
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS459323
- Product descriptionZebularine ≥98%
- Packaging250mg
- Price$33
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS459323
- Product descriptionZebularine ≥98%
- Packaging1g
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS459323
- Product descriptionZebularine ≥98%
- Packaging5g
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1254
- Product descriptionZebularine 99%
- Packaging10mg
- Price$104.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberND09503
- Product description4-Deoxyuridine
- Packaging100mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberND09503
- Product description4-Deoxyuridine
- Packaging250mg
- Price$132.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberND09503
- Product description4-Deoxyuridine
- Packaging500mg
- Price$210
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2817AH | Zebularine | 250mg | $228 | 2021-12-16 | Buy |
| ApexBio Technology | A1915 | Zebularine | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A1915 | Zebularine | 10mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | A1915 | Zebularine | 50mg | $280 | 2021-12-16 | Buy |
| Apolloscientific | BIA8416 | Zebularine | 50mg | $203 | 2021-12-16 | Buy |
| Apolloscientific | BIA8416 | Zebularine | 100mg | $319 | 2021-12-16 | Buy |
| Arctom | AS459323 | Zebularine ≥98% | 5mg | $8 | 2021-12-16 | Buy |
| Arctom | AS459323 | Zebularine ≥98% | 10mg | $10 | 2021-12-16 | Buy |
| Arctom | AS459323 | Zebularine ≥98% | 50mg | $17 | 2021-12-16 | Buy |
| Arctom | AS459323 | Zebularine ≥98% | 250mg | $33 | 2021-12-16 | Buy |
| Arctom | AS459323 | Zebularine ≥98% | 1g | $72 | 2021-12-16 | Buy |
| Arctom | AS459323 | Zebularine ≥98% | 5g | $238 | 2021-12-16 | Buy |
| Axon Medchem | Axon1254 | Zebularine 99% | 10mg | $104.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | ND09503 | 4-Deoxyuridine | 100mg | $63 | 2021-12-16 | Buy |
| Biosynth Carbosynth | ND09503 | 4-Deoxyuridine | 250mg | $132.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | ND09503 | 4-Deoxyuridine | 500mg | $210 | 2021-12-16 | Buy |
Properties
Melting point :160-162?C
Boiling point :499.0±55.0 °C(Predicted)
Density :1.73±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 16 mg/mL, soluble
form :solid
pka :13.48±0.70(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChIKey :RPQZTTQVRYEKCR-WCTZXXKLSA-N
Boiling point :499.0±55.0 °C(Predicted)
Density :1.73±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 16 mg/mL, soluble
form :solid
pka :13.48±0.70(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChIKey :RPQZTTQVRYEKCR-WCTZXXKLSA-N
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Zebularine, a cytidine analog, is a DNA methylation inhibitor that acts by forming a covalent complex with DNA methyltransferases (DNMTs). By stabilizing the binding of DNMTs to DNA, zebularine hinders methylation and decreases dissociation, trapping DNMT and preventing its turnover. Zebularine preferentially targets cancer cells in various human carcinoma cell lines demonstrating IC20 values of 20, 10, 20, and 5 μM for reducing proliferation of TK6, Jurkat, KG-1, and HCT116 cells, respectively. Zebularine exhibits low toxicity in mice even after prolonged administration (0.2 mg/mL drinking water for 113 days in a mouse intestinal cancer model).More related product prices
5-METHYLCYTIDINE 34654-81-4 URAPIDIL 5-METHYL- BETA-PSEUDOURIDINE 6972-27-6 6-[[3-[4-(4-Methoxyphenyl)-1-piperazinyl]propyl]aMino]-1,3-diMethyl-2,4(1H,3H)-pyriMidinedione Alisol B acetate Anisodine hydrobromide Zearalenone N4-Acetylcytidine CYTIDINE 3'-MONOPHOSPHATE N-Benzoylcytidine CYTIDINE SULFATE Cytidine Cytidylic acidRelated product price
- 5-METHYLCYTIDINE
$10-935 - 34654-81-4
$55-2148.3 - URAPIDIL 5-METHYL-
$123-1776.68
