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ChemicalBook >> CAS DataBase List >> Vinblastine sulfate

Vinblastine sulfate

Vinblastine sulfate price.
  • $24.55 - $1920
  • Product name: Vinblastine sulfate
  • CAS: 143-67-9
  • MF: C46H60N4O13S
  • MW: 909.05
  • EINECS:205-606-0
  • MDL Number:MFCD00082457
  • Synonyms:29060le ;nsc49842 ;rozevinsulfate ;velbe ;vincaleukoblastine,sulfate(1:1)(salt) ;Vinblastine, sulphate salt;VLB, Vincaleukoblastine sulphate salt;Vinblastine Sulphate USP
61 prices
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Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
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  • v0300000
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-V0013-M025
  • Product descriptionVinblastine sulfate ≥97%(HPLC)
  • Packaging25mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1256
  • Product descriptionVinblastine sulfate 98%
  • Packaging0.5g
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF345
  • Product descriptionVinblastine sulfate
  • Packaging10g
  • Price$1157
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63598
  • Product descriptionVinblastine sulfate 98%
  • Packaging10mg
  • Price$114
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63598
  • Product descriptionVinblastine sulfate 98%
  • Packaging50mg
  • Price$417
  • Updated2023-06-20
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3920
  • Product descriptionVinblastine sulfate
  • Packaging10mM(in 1mL DMSO)
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3920
  • Product descriptionVinblastine sulfate
  • Packaging10mg
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3920
  • Product descriptionVinblastine sulfate
  • Packaging25mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3920
  • Product descriptionVinblastine sulfate
  • Packaging50mg
  • Price$251
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY072852
  • Product descriptionVinblastinesulfate,98%
  • Packaging10mg
  • Price$24.55
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN90146
  • Product descriptionVinblastine sulfate
  • Packaging20mg
  • Price$100
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1012
  • Product descriptionVinblastine Sulfate
  • Packaging25mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1012
  • Product descriptionVinblastine Sulfate
  • Packaging50mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1012
  • Product descriptionVinblastine Sulfate
  • Packaging100mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1012
  • Product descriptionVinblastine Sulfate
  • Packaging1g
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545952
  • Product descriptionVinblastine sulfate >98%
  • Packaging5mg
  • Price$151.3
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-V0013-M025 Vinblastine sulfate ≥97%(HPLC) 25mg $124 2021-12-16 Buy
AHH API-1256 Vinblastine sulfate 98% 0.5g $810 2021-12-16 Buy
AK Scientific F345 Vinblastine sulfate 10g $1157 2021-12-16 Buy
Alfa Aesar J63598 Vinblastine sulfate 98% 10mg $114 2023-06-20 Buy
Alfa Aesar J63598 Vinblastine sulfate 98% 50mg $417 2023-06-20 Buy
ApexBio Technology A3920 Vinblastine sulfate 10mM(in 1mL DMSO) $77 2021-12-16 Buy
ApexBio Technology A3920 Vinblastine sulfate 10mg $81 2021-12-16 Buy
ApexBio Technology A3920 Vinblastine sulfate 25mg $168 2021-12-16 Buy
ApexBio Technology A3920 Vinblastine sulfate 50mg $251 2021-12-16 Buy
Arctom SY072852 Vinblastinesulfate,98% 10mg $24.55 2021-12-16 Buy
Arctom CFN90146 Vinblastine sulfate 20mg $100 2021-12-16 Buy
AvaChem 1012 Vinblastine Sulfate 25mg $49 2021-12-16 Buy
AvaChem 1012 Vinblastine Sulfate 50mg $79 2021-12-16 Buy
AvaChem 1012 Vinblastine Sulfate 100mg $90 2021-12-16 Buy
AvaChem 1012 Vinblastine Sulfate 1g $420 2021-12-16 Buy
Biorbyt Ltd orb545952 Vinblastine sulfate >98% 5mg $151.3 2021-12-16 Buy

Properties

Melting point :267 °C (dec.)(lit.)
alpha :-21.7 º (c=2, CH3OH 21 ºC)
storage temp. :2-8°C
solubility :H2O: 10 mg/mL
form :powder
color :white
PH :3.5~5.0 (1g/l, 25℃)
Water Solubility :>=1 g/100 mL at 24.5 ºC
Merck :13,10044
BRN :3659812
InChIKey :KDQAABAKXDWYSZ-PNYVAJAMSA-N
CAS DataBase Reference :143-67-9(CAS DataBase Reference)
IARC :3 (Vol. 26, Sup 7) 1987
EPA Substance Registry System :Vinblastine sulfate (143-67-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Vinblastine, derived from C. roseus, also known as V. rosea, a Madagascar periwinkle, is an antimicrotubule drug used to treat certain cancers, including Hodgkin’s lymphoma, non-small cell lung, breast, head and neck, and testicular cancer. Like its chemical analog vincristine, vinblastine binds tubulin, inhibiting the assembly of microtubules and causing M phase-specific cell cycle arrest by disrupting microtubule assembly and proper formation of the mitotic spindle. It has been shown to inhibit steady-state tubulin addition to microtubules with a Ki value of 0.18 μM, inhibit B16 melanoma cell proliferation with an IC50 value of 1 nM, and produce complete inhibition of L-cell proliferation at 40 nM. Vinblastine is reported to be an effective component of certain chemotherapy regimens, particularly when used with bleomycin and methotrexate in vinblastine, bleomycin, and methotrexate combination chemotherapy for Stage IA or IIA Hodgkin lymphomas.

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