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ChemicalBook >> CAS DataBase List >> VU0155041 sodium salt

VU0155041 sodium salt

VU0155041 sodium salt price.
  • $32 - $305
  • Product name: VU0155041 sodium salt
  • CAS: 1259372-69-4
  • MF: C14H14Cl2NNaO3
  • MW: 338.162
  • EINECS:
  • MDL Number:
  • Synonyms:VU0155041 sodium salt;cis-2-[[(3,5-Dichlorophenyl)amino]carbonyl]cyclohexanecarboxylicacidsodiumsalt;VU0155041 sodium;VU-0155041 sodium,VU0155041 sodium;VU0155041 sodium salt, PAM for mGluR4
10 prices
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Brand
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerApexBio Technology
  • Product numberB7357
  • Product descriptionVU0155041sodiumsalt
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7357
  • Product descriptionVU0155041sodiumsalt
  • Packaging50mg
  • Price$261
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21775
  • Product descriptionVU0155041 (sodium salt) ≥98%
  • Packaging5mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21775
  • Product descriptionVU0155041 (sodium salt) ≥98%
  • Packaging10mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21775
  • Product descriptionVU0155041 (sodium salt) ≥98%
  • Packaging50mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number3311
  • Product descriptionVU0155041sodiumsalt ≥98%(HPLC)
  • Packaging10
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3311
  • Product descriptionVU0155041sodiumsalt ≥98%(HPLC)
  • Packaging50
  • Price$273
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberV787595
  • Product descriptionVU0155041SodiumSalt
  • Packaging25mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number257054
  • Product descriptionVU 0155041 sodium salt
  • Packaging10mg
  • Price$305
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number468767
  • Product descriptionVU 0155041 Sodium Salt
  • Packaging5mg
  • Price$305
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B7357 VU0155041sodiumsalt 10mg $85 2021-12-16 Buy
ApexBio Technology B7357 VU0155041sodiumsalt 50mg $261 2021-12-16 Buy
Cayman Chemical 21775 VU0155041 (sodium salt) ≥98% 5mg $32 2024-03-01 Buy
Cayman Chemical 21775 VU0155041 (sodium salt) ≥98% 10mg $57 2024-03-01 Buy
Cayman Chemical 21775 VU0155041 (sodium salt) ≥98% 50mg $169 2024-03-01 Buy
Tocris 3311 VU0155041sodiumsalt ≥98%(HPLC) 10 $74 2021-12-16 Buy
Tocris 3311 VU0155041sodiumsalt ≥98%(HPLC) 50 $273 2021-12-16 Buy
TRC V787595 VU0155041SodiumSalt 25mg $105 2021-12-16 Buy
Usbiological 257054 VU 0155041 sodium salt 10mg $305 2021-12-16 Buy
Usbiological 468767 VU 0155041 Sodium Salt 5mg $305 2021-12-16 Buy

Properties

storage temp. :Desiccate at RT
solubility :DMSO: 1 mg/ml; PBS (pH 7.2): 2 mg/ml
form :Powder
Water Solubility :Soluble to 25 mM in water

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

VU0155041 is a positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4) with an EC50 value of 2.5 μM for glutamate response in a thallium flux assay. It is selective for mGluR4, exhibiting no effect on radioligand binding at 67 G protein-coupled receptors, ion channels, and transporters, and lacking antagonist activity at NMDA receptors in striatal medium spiny neurons at a concentration of 10 μM. In vivo, VU0155041 decreases catalepsy induced by haloperidol and reverses askinesias induced by reserpine in rat models of Parkinson’s disease. Chronic treatment with VU0155041 restores social behavior in the Oprm-/- mouse model of autism. It also increases the percentage of time spent in the open arms of the elevated plus maze, a measure of decreased anxiety, in mice.