Tacrolimus Monohydrate
- $11 - $2419.1
- Product name: Tacrolimus Monohydrate
- CAS: 109581-93-3
- MF: C44H71NO13
- MW: 822.05
- EINECS:617-559-7
- MDL Number:MFCD11045918
- Synonyms:15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;TACROLIMUS HYDRATE/TSUKUBAENOLIDE HYDRATE;(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone;Tacrolimus (150 mg);(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-Methoxycyclohexyl]-1-Methylethenyl]-14,16-diMethoxy-4,10,12,18-tetraMethyl-8-(2-propen-1-yl)-;FK-506 monohydrate, >=98%;Tacrolimus /FK506 monohydrate;,8s*,9e,12r*,14r*,15s*,16r*,18s*,19s*,26ar*))-
44 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Biosynth Carbosynth
- Chem-Impex
- ChemScene
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- Y0001926
- 5mg
- Y0001933
- 1mg
- 10
- 10mg
- 50mg
- 100mg
- 150mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5G
- 10g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0047-M005
- Product descriptionFK-506 ≥98%(HPLC)
- Packaging5mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ99439
- Product descriptionTacrolimus monohydrate
- Packaging50mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA377737
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+%
- Packaging5mg
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA377737
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+%
- Packaging10mg
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA377737
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+%
- Packaging50mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA377737
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+%
- Packaging100mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA377737
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+%
- Packaging250mg
- Price$78
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA377737
- Product description(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+%
- Packaging1g
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004310
- Product descriptionTACROLIMUS HYDRATE 95.00%
- Packaging10MG
- Price$665.81
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545826
- Product descriptionFK-506 >98%
- Packaging10mg
- Price$151.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545826
- Product descriptionFK-506 >98%
- Packaging50mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61029
- Product descriptionFK-506 >99% pure
- Packaging50mg
- Price$379.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61029
- Product descriptionFK-506 >99% pure
- Packaging100mg
- Price$430.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61029
- Product descriptionFK-506 >99% pure
- Packaging200mg
- Price$574.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61029
- Product descriptionFK-506 >99% pure
- Packaging500mg
- Price$618.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61029
- Product descriptionFK-506 >99% pure
- Packaging1g
- Price$855.1
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CN2-0047-M005 | FK-506 ≥98%(HPLC) | 5mg | $25 | 2021-12-16 | Buy |
AK Scientific | J99439 | Tacrolimus monohydrate | 50mg | $90 | 2021-12-16 | Buy |
Ambeed | A377737 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+% | 5mg | $11 | 2021-12-16 | Buy |
Ambeed | A377737 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+% | 10mg | $14 | 2021-12-16 | Buy |
Ambeed | A377737 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+% | 50mg | $23 | 2021-12-16 | Buy |
Ambeed | A377737 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+% | 100mg | $39 | 2021-12-16 | Buy |
Ambeed | A377737 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+% | 250mg | $78 | 2021-12-16 | Buy |
Ambeed | A377737 | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetronemonohydrate 98+% | 1g | $200 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0004310 | TACROLIMUS HYDRATE 95.00% | 10MG | $665.81 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545826 | FK-506 >98% | 10mg | $151.3 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545826 | FK-506 >98% | 50mg | $357 | 2021-12-16 | Buy |
Biorbyt Ltd | orb61029 | FK-506 >99% pure | 50mg | $379.1 | 2021-12-16 | Buy |
Biorbyt Ltd | orb61029 | FK-506 >99% pure | 100mg | $430.1 | 2021-12-16 | Buy |
Biorbyt Ltd | orb61029 | FK-506 >99% pure | 200mg | $574.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb61029 | FK-506 >99% pure | 500mg | $618.8 | 2021-12-16 | Buy |
Biorbyt Ltd | orb61029 | FK-506 >99% pure | 1g | $855.1 | 2021-12-16 | Buy |
Properties
Melting point :127-129°
alpha :D23 -84.4° (c = 1.02 in chloroform)
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL
form :powder
color :White to Almost white
Merck :14,9025
InChIKey :NWJQLQGQZSIBAF-MLAUYUEBSA-N
alpha :D23 -84.4° (c = 1.02 in chloroform)
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL
form :powder
color :White to Almost white
Merck :14,9025
InChIKey :NWJQLQGQZSIBAF-MLAUYUEBSA-N
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Danger | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
FK-506 monohydrate is a potent immunosuppressant, neuroprotective and neuroregenerative, as well as an in vitro T cell proliferation blocker. This compound disrupts calcineurin-mediated signal transduction in T lymphocytes and interacts with its FK-506-binding protein-12 (FKBP12).Related product price
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