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ChemicalBook >> CAS DataBase List >> TUG 891

TUG 891

TUG 891 price.
  • $34 - $1475
  • Product name: TUG 891
  • CAS: 1374516-07-0
  • MF: C23H21FO3
  • MW: 364.41
  • EINECS:
  • MDL Number:MFCD22421654
  • Synonyms:TUG 891;4-[(4-Fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoic acid;CS-2448;TUG 891;TUG-891;Benzenepropanoic acid, 4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-;3-(4-{[5-fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoic acid;Inhibitor,inhibit,Free Fatty Acid Receptor,TUG-891,FFAR;3-{4-[(4-Fluoro-4'-methyl-2-biphenylyl)methoxy]phenyl}propanoic acid
27 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 5mg
  • 10
  • 1mg
  • 50
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number6118DN
  • Product description3-(4-{[5-Fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoicacid
  • Packaging10mg
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6118DN
  • Product description3-(4-{[5-Fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoicacid
  • Packaging25mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA844329
  • Product descriptionTUG-891 95+%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA844329
  • Product descriptionTUG-891 95+%
  • Packaging10mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA844329
  • Product descriptionTUG-891 95+%
  • Packaging25mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA844329
  • Product descriptionTUG-891 95+%
  • Packaging50mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5651
  • Product descriptionTUG891
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5651
  • Product descriptionTUG891
  • Packaging25mg
  • Price$356
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17035
  • Product descriptionTUG-891 ≥98%
  • Packaging1mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17035
  • Product descriptionTUG-891 ≥98%
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17035
  • Product descriptionTUG-891 ≥98%
  • Packaging10mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17035
  • Product descriptionTUG-891 ≥98%
  • Packaging25mg
  • Price$362
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6138
  • Product descriptionTUG-891 99.20%
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6138
  • Product descriptionTUG-891 99.20%
  • Packaging10mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6138
  • Product descriptionTUG-891 99.20%
  • Packaging25mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6138
  • Product descriptionTUG-891 99.20%
  • Packaging50mg
  • Price$480
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6118DN 3-(4-{[5-Fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoicacid 10mg $282 2021-12-16 Buy
AK Scientific 6118DN 3-(4-{[5-Fluoro-2-(4-methylphenyl)phenyl]methoxy}phenyl)propanoicacid 25mg $500 2021-12-16 Buy
Ambeed A844329 TUG-891 95+% 5mg $73 2021-12-16 Buy
Ambeed A844329 TUG-891 95+% 10mg $134 2021-12-16 Buy
Ambeed A844329 TUG-891 95+% 25mg $175 2021-12-16 Buy
Ambeed A844329 TUG-891 95+% 50mg $228 2021-12-16 Buy
ApexBio Technology B5651 TUG891 10mg $140 2021-12-16 Buy
ApexBio Technology B5651 TUG891 25mg $356 2021-12-16 Buy
Cayman Chemical 17035 TUG-891 ≥98% 1mg $34 2024-03-01 Buy
Cayman Chemical 17035 TUG-891 ≥98% 5mg $100 2024-03-01 Buy
Cayman Chemical 17035 TUG-891 ≥98% 10mg $166 2024-03-01 Buy
Cayman Chemical 17035 TUG-891 ≥98% 25mg $362 2024-03-01 Buy
ChemScene CS-6138 TUG-891 99.20% 5mg $96 2021-12-16 Buy
ChemScene CS-6138 TUG-891 99.20% 10mg $144 2021-12-16 Buy
ChemScene CS-6138 TUG-891 99.20% 25mg $288 2021-12-16 Buy
ChemScene CS-6138 TUG-891 99.20% 50mg $480 2021-12-16 Buy

Properties

Boiling point :540.8±50.0 °C(Predicted)
Density :1.199±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO:30.0(Max Conc. mg/mL);82.32(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);13.72(Max Conc. mM)
Ethanol:1.0(Max Conc. mg/mL);2.74(Max Conc. mM) form :Powder
pka :4.70±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GPR120 (free fatty acid receptor 4; FFAR4) is a G protein-coupled receptor (GPCR) expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. ω-3 Fatty acids, such as docosahexaenoic acid and eicosapentaenoic acid , initiate GPR120 signaling resulting in inhibition of toll-like receptor and TNF-α inflammatory signaling pathways in a β-arrestin2/TAB1 dependent manner. TUG-891 is a potent and selective agonist of GPR120 with pEC50 values of 7.36 and 7.77 for human and mouse GPR120, respectively. It activates GPR40 (FFAR1) with a pEC50 value of 4.19 and shows no activity at GPR41 (FFAR3) or GPR43 (FFAR2).

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