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ChemicalBook >> CAS DataBase List >> Ramatroban

Ramatroban

Ramatroban price.
  • $29 - $2714.25
  • Product name: Ramatroban
  • CAS: 116649-85-5
  • MF: C21H21FN2O4S
  • MW: 416.47
  • EINECS:
  • MDL Number:MFCD00887606
  • Synonyms:BAY-U3405;3R-[[(4-FLUOROPHENYL)SULFONYL]AMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-PROPANOIC ACID;(3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propionic acid;3-[(3R)-3-(4-Fluorophenylsulfonylamino)-1,2,3,4-tetrahydro-9H-carbazole-9-yl]propionic acid;(R)-3-(3-(4-fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoic acid;RAFFINOSE UNDECAACETATE, D-(+)-(RG);(3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoicacid;RaMatroban(BAY-u3405)
38 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1MG
  • 5mg
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  • 100mg
  • 250mg
  • 50
  • 1G
  • 10g
  • ManufacturerAK Scientific
  • Product numberSYN5571
  • Product descriptionRamatroban
  • Packaging100mg
  • Price$1296
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA436709
  • Product description(R)-3-(3-(4-Fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoicacid 98+%
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA436709
  • Product description(R)-3-(3-(4-Fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoicacid 98+%
  • Packaging25mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA436709
  • Product description(R)-3-(3-(4-Fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoicacid 98+%
  • Packaging50mg
  • Price$101
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004035
  • Product descriptionRAMATROBAN 95.00%
  • Packaging1MG
  • Price$135.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004035
  • Product descriptionRAMATROBAN 95.00%
  • Packaging1G
  • Price$2714.25
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3753
  • Product descriptionBAYu3405
  • Packaging5mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3753
  • Product descriptionBAYu3405
  • Packaging10mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3753
  • Product descriptionBAYu3405
  • Packaging50mg
  • Price$851
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2613
  • Product descriptionRamatroban
  • Packaging10g
  • Price$1590
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2613
  • Product descriptionRamatroban
  • Packaging1g
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2613
  • Product descriptionRamatroban
  • Packaging250mg
  • Price$229
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2613
  • Product descriptionRamatroban
  • Packaging100mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2613
  • Product descriptionRamatroban
  • Packaging25mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2613
  • Product descriptionRamatroban
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2613
  • Product descriptionRamatroban
  • Packaging5mg
  • Price$29
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5571 Ramatroban 100mg $1296 2021-12-16 Buy
Ambeed A436709 (R)-3-(3-(4-Fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoicacid 98+% 10mg $59 2021-12-16 Buy
Ambeed A436709 (R)-3-(3-(4-Fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoicacid 98+% 25mg $77 2021-12-16 Buy
Ambeed A436709 (R)-3-(3-(4-Fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoicacid 98+% 50mg $101 2021-12-16 Buy
American Custom Chemicals Corporation API0004035 RAMATROBAN 95.00% 1MG $135.45 2021-12-16 Buy
American Custom Chemicals Corporation API0004035 RAMATROBAN 95.00% 1G $2714.25 2021-12-16 Buy
ApexBio Technology C3753 BAYu3405 5mg $108 2021-12-16 Buy
ApexBio Technology C3753 BAYu3405 10mg $187 2021-12-16 Buy
ApexBio Technology C3753 BAYu3405 50mg $851 2021-12-16 Buy
AvaChem 2613 Ramatroban 10g $1590 2021-12-16 Buy
AvaChem 2613 Ramatroban 1g $490 2021-12-16 Buy
AvaChem 2613 Ramatroban 250mg $229 2021-12-16 Buy
AvaChem 2613 Ramatroban 100mg $119 2021-12-16 Buy
AvaChem 2613 Ramatroban 25mg $59 2021-12-16 Buy
AvaChem 2613 Ramatroban 10mg $39 2021-12-16 Buy
AvaChem 2613 Ramatroban 5mg $29 2021-12-16 Buy

Properties

Melting point :134-135°
alpha :D +70.1° (c = 1.0 in methanol)
Boiling point :654.7±65.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: ≥40mg/mL
form :solid
pka :4.60±0.10(Predicted)
color :white
CAS DataBase Reference :116649-85-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The biological effects of prostaglandin D2 (PGD2; ) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and DP2/CRTH2. BAY-u3405 (Ramatroban) is an approved human medication for the treatment of allergic rhinitis that has documented activity as an antagonist of the thromboxane receptor (TP receptor). BAY-u3405 is also an antagonist of the DP2 receptor with IC50 values of 100-170 nM. BAY-u3405 is more potent at the DP2 receptor than the TP receptor by 4-5 fold. BAY-u3405 is therefore a useful tool for the elucidation of PGD2/DP2 function in eosinophils, basophils, and other cells of the TH2 cell-type.

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