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ChemicalBook >> CAS DataBase List >> Pazopanib

Pazopanib

Pazopanib price.
  • $28 - $1871.1
  • Product name: Pazopanib
  • CAS: 444731-52-6
  • MF: C21H23N7O2S
  • MW: 437.52
  • EINECS:251-228-4
  • MDL Number:MFCD11616589
  • Synonyms:Pazopanib for research;Pazopanib;Pazopanib(GW786034);5-(4-((2,3-diMethyl-3,3a-dihydro-2H-indazol-6-yl)(Methyl)aMino)pyriMidin-2-ylaMino)-2-MethylbenzenesulfonaMide;5-[(4-{[(2,3-diMethyl-2H-indazol-6-yl)Methyl]aMino}pyriMidin-2-yl)aMino]-2-Methylbenzene-1-sulfonaMide;5-({4-[(2,3-diMethyl-2H-indazol-6-yl)(Methyl)aMino]pyriMidin-2-yl}aMino)-2-MethylbenzenesulfonaMide 5-(4-(N-(2,3-diMethyl-2H-indazole-6-yl)- N-MethylaMino)pyriMidine-2-ylaMino)-2-MethylbenzenesulfonaMide;GW786034; VOTRIENT;BenzenesulfonaMide, 5-[[4-[(2,3-diMethyl-2H-indazol-6-yl)MethylaMino]-2-pyriMidinyl]aMino]-2-Methyl-
47 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Chemtos
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1unit
  • 5mg
  • 10MG
  • 20mg
  • 25mg
  • 50mg
  • 100MG
  • 200mg
  • 250mg
  • 500mg
  • 10mM(in 1mL DMSO)
  • 1g
  • 2g
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3746-M050
  • Product descriptionPazopanib(freebase) ≥98%(HPLC)
  • Packaging50mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberA822
  • Product descriptionPazopanib
  • Packaging5g
  • Price$1061
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024403
  • Product descriptionPAZOPANIB 95.00%
  • Packaging10MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0024403
  • Product descriptionPAZOPANIB 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3022
  • Product descriptionPazopanib(GW-786034)
  • Packaging500mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3022
  • Product descriptionPazopanib(GW-786034)
  • Packaging100mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3022
  • Product descriptionPazopanib(GW-786034)
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3022
  • Product descriptionPazopanib(GW-786034)
  • Packaging25mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3022
  • Product descriptionPazopanib(GW-786034)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60164
  • Product descriptionPazopanib ≥98%
  • Packaging20mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2631
  • Product descriptionPazopanib
  • Packaging10mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2631
  • Product descriptionPazopanib
  • Packaging25mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2631
  • Product descriptionPazopanib
  • Packaging100mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2631
  • Product descriptionPazopanib
  • Packaging1g
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546004
  • Product descriptionPazopanib >98%
  • Packaging5mg
  • Price$173.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546004
  • Product descriptionPazopanib >98%
  • Packaging25mg
  • Price$455.6
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3746-M050 Pazopanib(freebase) ≥98%(HPLC) 50mg $75 2021-12-16 Buy
AK Scientific A822 Pazopanib 5g $1061 2021-12-16 Buy
American Custom Chemicals Corporation API0024403 PAZOPANIB 95.00% 10MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation API0024403 PAZOPANIB 95.00% 100MG $1871.1 2021-12-16 Buy
ApexBio Technology A3022 Pazopanib(GW-786034) 500mg $480 2021-12-16 Buy
ApexBio Technology A3022 Pazopanib(GW-786034) 100mg $150 2021-12-16 Buy
ApexBio Technology A3022 Pazopanib(GW-786034) 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A3022 Pazopanib(GW-786034) 25mg $50 2021-12-16 Buy
ApexBio Technology A3022 Pazopanib(GW-786034) 1unit $28 2021-12-16 Buy
Arctom CFN60164 Pazopanib ≥98% 20mg $148 2021-12-16 Buy
AvaChem 2631 Pazopanib 10mg $29 2021-12-16 Buy
AvaChem 2631 Pazopanib 25mg $39 2021-12-16 Buy
AvaChem 2631 Pazopanib 100mg $75 2021-12-16 Buy
AvaChem 2631 Pazopanib 1g $135 2021-12-16 Buy
Biorbyt Ltd orb546004 Pazopanib >98% 5mg $173.4 2021-12-16 Buy
Biorbyt Ltd orb546004 Pazopanib >98% 25mg $455.6 2021-12-16 Buy

Properties

Melting point :285-289°C (dec.)
Boiling point :728.8±70.0 °C(Predicted)
Density :1.40
Flash point :359℃
storage temp. :Refrigerator
solubility :Aqueous Acid (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka :10.19±0.60(Predicted)
form :Yellow powder.
color :White to Beige

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment

Description

Pazopanib is a broad spectrum tyrosine kinase inhibitor that blocks angiogenesis through its actions on VEGF receptors (VEGFRs). It has low nanomolar efficacy against VEGFR1 (FLT1), VEGFR2, VEGFR3 (FLT4), and KIT, as well as receptors for macrophage colony-stimulating factor 1 and platelet-derived growth factor. Pazopanib is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 and, to a lesser extent, CYP1A2 and CYP2C8. It is effective in vivo and is useful in the management of certain types of cancer.

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