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ChemicalBook >> CAS DataBase List >> NVS-PAK1-1

NVS-PAK1-1

NVS-PAK1-1 price.
  • $43 - $2525
  • Product name: NVS-PAK1-1
  • CAS: 1783816-74-9
  • MF: C23H25ClF3N5O
  • MW: 479.93
  • EINECS:
  • MDL Number:MFCD30723183
  • Synonyms:NVS-PAK1-1;(3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N-isopropylpyrrolidine-1-carboxamide;NVS-PAK1-1;NVS-PAK11;NVS-PAK1 1;1-Pyrrolidinecarboxamide, 3-[[2-chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl]amino]-N-(1-methylethyl)-, (3S)-;NVS-PAK1-1 >=98% (HPLC);NVS-PAK11Chemicalbook;(S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide;Inhibitor,p21 activated kinases,NVS PAK1 1,inhibit,PAK,NVS-PAK-1-1,NVSPAK11
26 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 25
  • 1mg
  • 5
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number9739EM
  • Product description(3S)-3-[[8-Chloro-11-(2,2-difluoroethyl)-3-fluoro-5H-benzo[b][1,4]benzodiazepin-6-ylidene]amino]-N-propan-2-ylpyrrolidine-1-carboxamide
  • Packaging5mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA605423
  • Product description(S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98%
  • Packaging1mg
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA605423
  • Product description(S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98%
  • Packaging5mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA605423
  • Product description(S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98%
  • Packaging10mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA605423
  • Product description(S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98%
  • Packaging25mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA605423
  • Product description(S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98%
  • Packaging50mg
  • Price$359
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA605423
  • Product description(S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98%
  • Packaging100mg
  • Price$528
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA605423
  • Product description(S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98%
  • Packaging250mg
  • Price$1049
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA605423
  • Product description(S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98%
  • Packaging1g
  • Price$2525
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19964
  • Product descriptionNVS-PAK1-1 ≥98%
  • Packaging5mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19964
  • Product descriptionNVS-PAK1-1 ≥98%
  • Packaging10mg
  • Price$218
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19964
  • Product descriptionNVS-PAK1-1 ≥98%
  • Packaging25mg
  • Price$481
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6916
  • Product descriptionNVS-PAK1-1 >99.0%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6916
  • Product descriptionNVS-PAK1-1 >99.0%
  • Packaging10mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6916
  • Product descriptionNVS-PAK1-1 >99.0%
  • Packaging25mg
  • Price$468
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6916
  • Product descriptionNVS-PAK1-1 >99.0%
  • Packaging50mg
  • Price$828
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9739EM (3S)-3-[[8-Chloro-11-(2,2-difluoroethyl)-3-fluoro-5H-benzo[b][1,4]benzodiazepin-6-ylidene]amino]-N-propan-2-ylpyrrolidine-1-carboxamide 5mg $233 2021-12-16 Buy
Ambeed A605423 (S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98% 1mg $43 2021-12-16 Buy
Ambeed A605423 (S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98% 5mg $86 2021-12-16 Buy
Ambeed A605423 (S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98% 10mg $156 2021-12-16 Buy
Ambeed A605423 (S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98% 25mg $276 2021-12-16 Buy
Ambeed A605423 (S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98% 50mg $359 2021-12-16 Buy
Ambeed A605423 (S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98% 100mg $528 2021-12-16 Buy
Ambeed A605423 (S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98% 250mg $1049 2021-12-16 Buy
Ambeed A605423 (S)-3-((2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl)amino)-N-isopropylpyrrolidine-1-carboxamide 98% 1g $2525 2021-12-16 Buy
Cayman Chemical 19964 NVS-PAK1-1 ≥98% 5mg $121 2024-03-01 Buy
Cayman Chemical 19964 NVS-PAK1-1 ≥98% 10mg $218 2024-03-01 Buy
Cayman Chemical 19964 NVS-PAK1-1 ≥98% 25mg $481 2024-03-01 Buy
ChemScene CS-6916 NVS-PAK1-1 >99.0% 5mg $120 2021-12-16 Buy
ChemScene CS-6916 NVS-PAK1-1 >99.0% 10mg $216 2021-12-16 Buy
ChemScene CS-6916 NVS-PAK1-1 >99.0% 25mg $468 2021-12-16 Buy
ChemScene CS-6916 NVS-PAK1-1 >99.0% 50mg $828 2021-12-16 Buy

Properties

Boiling point :697.8±55.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF: 50 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 50 mg/ml; Ethanol: 20 mg/ml
pka :14.02±0.40(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.

Description

NVS PAK1 1 is one of potent and selective allosteric PAK1 inhibitors.