MM-102
- $32 - $3580.2
- Product name: MM-102
- CAS: 1417329-24-8
- MF: C35H49F2N7O4
- MW: 669.8
- EINECS:-0
- MDL Number:MFCD28015099
- Synonyms:MM-102;Cyclopentanecarboxamide, 1-[[(2S)-5-[(aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-;HMTase Inhibitor IX;1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]cyclopentanecarboxamide];CS-2007;HMTASE INHIBITOR IX;MM102;MM 102;MM-102;MM-102 TFA Salt;MM-102 USP/EP/BP
25 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 20mg
- 25mg
- 100mg
- 250mg
- 1000mg
- 1g
- ManufacturerAK Scientific
- Product number2559AH
- Product description1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide
- Packaging5mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2559AH
- Product description1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide
- Packaging10mg
- Price$353
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2559AH
- Product description1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide
- Packaging25mg
- Price$691
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1582
- Product descriptionMM-102
- Packaging2mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1582
- Product descriptionMM-102
- Packaging5mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1582
- Product descriptionMM-102
- Packaging20mg
- Price$469
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181379
- Product descriptionMM-102 >98%
- Packaging1000mg
- Price$3580.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181379
- Product descriptionMM-102 >98%
- Packaging250mg
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181379
- Product descriptionMM-102 >98%
- Packaging100mg
- Price$986
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17699
- Product descriptionMM-102 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17699
- Product descriptionMM-102 ≥98%
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17699
- Product descriptionMM-102 ≥98%
- Packaging10mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17699
- Product descriptionMM-102 ≥98%
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31003561
- Product descriptionMM-102 98+%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003561
- Product descriptionMM-102 98+%
- Packaging10mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003561
- Product descriptionMM-102 98+%
- Packaging25mg
- Price$410
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2559AH | 1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide | 5mg | $252 | 2021-12-16 | Buy |
AK Scientific | 2559AH | 1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide | 10mg | $353 | 2021-12-16 | Buy |
AK Scientific | 2559AH | 1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide | 25mg | $691 | 2021-12-16 | Buy |
ApexBio Technology | B1582 | MM-102 | 2mg | $68 | 2021-12-16 | Buy |
ApexBio Technology | B1582 | MM-102 | 5mg | $140 | 2021-12-16 | Buy |
ApexBio Technology | B1582 | MM-102 | 20mg | $469 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181379 | MM-102 >98% | 1000mg | $3580.2 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181379 | MM-102 >98% | 250mg | $1802 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181379 | MM-102 >98% | 100mg | $986 | 2021-12-16 | Buy |
Cayman Chemical | 17699 | MM-102 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 17699 | MM-102 ≥98% | 5mg | $139 | 2024-03-01 | Buy |
Cayman Chemical | 17699 | MM-102 ≥98% | 10mg | $230 | 2024-03-01 | Buy |
Cayman Chemical | 17699 | MM-102 ≥98% | 25mg | $533 | 2024-03-01 | Buy |
Crysdot | CD31003561 | MM-102 98+% | 5mg | $120 | 2021-12-16 | Buy |
Crysdot | CD31003561 | MM-102 98+% | 10mg | $200 | 2021-12-16 | Buy |
Crysdot | CD31003561 | MM-102 98+% | 25mg | $410 | 2021-12-16 | Buy |
Properties
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Store at -20° C
solubility :insoluble in H2O; ≥22.6 mg/mL in EtOH; ≥67 mg/mL in DMSO
form :Powder
pka :12.90±0.20(Predicted)
color :White to off-white
storage temp. :Store at -20° C
solubility :insoluble in H2O; ≥22.6 mg/mL in EtOH; ≥67 mg/mL in DMSO
form :Powder
pka :12.90±0.20(Predicted)
color :White to off-white
Safety Information
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. It serves as a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3 at lysine 4 to upregulate transcription. MM-102 is a potent WDR5/MLL interaction inhibitor (IC50 = 2.4 nM). It has been shown to block MLL1 methyltransferase activity, reducing the expression of HoxA9 and Meis-1 genes, which are both critical MLL1 target genes in MLL1 fusion protein-mediated leukemogenesis. MM-102 can also inhibit cell growth and induce apoptosis in leukemia cells harboring MLL1 fusion proteins.Related product price
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