L-KYNURENINE
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- $37 - $1637.71
- Product name: L-KYNURENINE
- CAS: 2922-83-0
- MF: C10H12N2O3
- MW: 208.21
- EINECS:
- MDL Number:MFCD00069912
- Synonyms:L-2-AMINO-3-(2-AMINOBENZOYL)PROPIONIC ACID;L-2-AMINO-4-[2-AMINOPHENYL]-4-OXOBUTANOIC ACID;L-KYNURENINE;L-kynurenine free base;β-Anthraniloyl-L-alanine;β-Anthraniloyl-L-alanine, L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid;L-Kynurenine Hydrate;(S)-2-Amino-4-oxo-4-(2-aminophenyl)butanoic acid
36 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- Alichem
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
Package
- 25mg
- 250mg
- 500mg
- 5G
- 50
- 10mM(in 1mL H2O)
- 10mg
- 50mg
- 100mg
- 1g
- 2.5G
- ManufacturerAK Scientific
- Product numberE641
- Product descriptionL-Kynurenine
- Packaging250mg
- Price$171
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60199
- Product descriptionL-Kynurenine
- Packaging50mg
- Price$79.7
- Updated2024-03-01
- Buy
- ManufacturerAlichem
- Product number2922830
- Product description(S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid
- Packaging250mg
- Price$412.34
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number2922830
- Product description(S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid
- Packaging1g
- Price$1060
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA965360
- Product description(S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid 98%
- Packaging100mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA965360
- Product description(S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid 98%
- Packaging250mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA965360
- Product description(S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid 98%
- Packaging1g
- Price$418
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0000073
- Product descriptionL-KYNURENINE 95.00%
- Packaging1G
- Price$846.73
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0000073
- Product descriptionL-KYNURENINE 95.00%
- Packaging2.5G
- Price$1144.66
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8612
- Product descriptionL-Kynurenine
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8612
- Product descriptionL-Kynurenine
- Packaging10mM(in 1mL H2O)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11305
- Product descriptionKynurenine ≥98%
- Packaging50mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11305
- Product descriptionKynurenine ≥98%
- Packaging100mg
- Price$70
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11305
- Product descriptionKynurenine ≥98%
- Packaging250mg
- Price$166
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11305
- Product descriptionKynurenine ≥98%
- Packaging500mg
- Price$276
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM126707
- Product description(S)-2-amino-4-(2-aminophenyl)-4-oxobutanoicacid 95%
- Packaging1g
- Price$337
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | E641 | L-Kynurenine | 250mg | $171 | 2021-12-16 | Buy |
| Alfa Aesar | J60199 | L-Kynurenine | 50mg | $79.7 | 2024-03-01 | Buy |
| Alichem | 2922830 | (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid | 250mg | $412.34 | 2021-12-16 | Buy |
| Alichem | 2922830 | (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid | 1g | $1060 | 2021-12-16 | Buy |
| Ambeed | A965360 | (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid 98% | 100mg | $66 | 2021-12-16 | Buy |
| Ambeed | A965360 | (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid 98% | 250mg | $147 | 2021-12-16 | Buy |
| Ambeed | A965360 | (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid 98% | 1g | $418 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0000073 | L-KYNURENINE 95.00% | 1G | $846.73 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0000073 | L-KYNURENINE 95.00% | 2.5G | $1144.66 | 2021-12-16 | Buy |
| ApexBio Technology | A8612 | L-Kynurenine | 50mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A8612 | L-Kynurenine | 10mM(in 1mL H2O) | $50 | 2021-12-16 | Buy |
| Cayman Chemical | 11305 | Kynurenine ≥98% | 50mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 11305 | Kynurenine ≥98% | 100mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 11305 | Kynurenine ≥98% | 250mg | $166 | 2024-03-01 | Buy |
| Cayman Chemical | 11305 | Kynurenine ≥98% | 500mg | $276 | 2024-03-01 | Buy |
| Chemenu | CM126707 | (S)-2-amino-4-(2-aminophenyl)-4-oxobutanoicacid 95% | 1g | $337 | 2021-12-16 | Buy |
Properties
Melting point :219 °C
Boiling point :466.6±45.0 °C(Predicted)
Density :1.343±0.06 g/cm3(Predicted)
refractive index :-33 ° (C=0.4, H2O)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml).
form :crystalline
pka :2.21±0.23(Predicted)
color :light yellow
optical activity :-30.525 (H2O)
Merck :14,5328
Stability :Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey :YGPSJZOEDVAXAB-QMMMGPOBSA-N
CAS DataBase Reference :2922-83-0(CAS DataBase Reference)
Boiling point :466.6±45.0 °C(Predicted)
Density :1.343±0.06 g/cm3(Predicted)
refractive index :-33 ° (C=0.4, H2O)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml).
form :crystalline
pka :2.21±0.23(Predicted)
color :light yellow
optical activity :-30.525 (H2O)
Merck :14,5328
Stability :Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey :YGPSJZOEDVAXAB-QMMMGPOBSA-N
CAS DataBase Reference :2922-83-0(CAS DataBase Reference)
Safety Information
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Description
Kynurenine is a product of constitutive tryptophan catabolism via tryptophan-2,3-dioxygenase in the liver and human gliomas that is associated with the suppression of antitumor immune responses. At 100 μM, kynurenine inhibits allogeneic T-cell proliferation and increases malignant U87 glioma cell invasion into a collagen matrix. Kynurenine activates the aryl hydrocarbon receptor (AhR) target gene CYP1A1 with an EC50 value of 12.3 μM and binds to AhR with an apparent Kd value of ~4 μM. Kynurenine is ultimately metabolized to quinolinic acid, a potent neurotoxin that acts as an NMDA agonist and has been described to be involved in neurodegenerative processes in the brain.More related product prices
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