GO 6976
- $49 - $2500
- Product name: GO 6976
- CAS: 136194-77-9
- MF: C24H18N4O
- MW: 378.43
- EINECS:200-258-5
- MDL Number:MFCD00236434
- Synonyms:InSolution? G? 6976 ;5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile;Go6976,5,6,7,13-Tetrahydro-13-Methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile;PD406976;12-(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO(2,3-A)PYRROLO(3,4-C)-CARBAZOLE;12-2(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE;GO 6976;G6976
24 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 500U
- 1g
- 1ml
- ManufacturerAK Scientific
- Product numberSYN5462
- Product descriptionGo6976
- Packaging50mg
- Price$1880
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8341
- Product descriptionGo6976
- Packaging5mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8341
- Product descriptionGo6976
- Packaging25mg
- Price$441
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60288
- Product descriptionGo6976
- Packaging5mg
- Price$338
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG168444
- Product descriptionGo 6976
- Packaging25mg
- Price$1750
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG168444
- Product descriptionGo 6976
- Packaging10mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG168444
- Product descriptionGo 6976
- Packaging5mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG168444
- Product descriptionGo 6976
- Packaging2mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG168444
- Product descriptionGo 6976
- Packaging1mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13310
- Product descriptionG? 6976 ≥98%
- Packaging500μg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13310
- Product descriptionG? 6976 ≥98%
- Packaging1mg
- Price$92
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13310
- Product descriptionG? 6976 ≥98%
- Packaging5mg
- Price$216
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0002498
- Product descriptionGo6976 99.34%
- Packaging1mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0002498
- Product descriptionGo6976 99.34%
- Packaging5mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN16571
- Product descriptionGo6976
- Packaging5mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN16571
- Product descriptionGo6976
- Packaging10mg
- Price$199
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5462 | Go6976 | 50mg | $1880 | 2021-12-16 | Buy |
ApexBio Technology | A8341 | Go6976 | 5mg | $147 | 2021-12-16 | Buy |
ApexBio Technology | A8341 | Go6976 | 25mg | $441 | 2021-12-16 | Buy |
Arctom | CFN60288 | Go6976 | 5mg | $338 | 2021-12-16 | Buy |
Biosynth Carbosynth | BG168444 | Go 6976 | 25mg | $1750 | 2021-12-16 | Buy |
Biosynth Carbosynth | BG168444 | Go 6976 | 10mg | $800 | 2021-12-16 | Buy |
Biosynth Carbosynth | BG168444 | Go 6976 | 5mg | $450 | 2021-12-16 | Buy |
Biosynth Carbosynth | BG168444 | Go 6976 | 2mg | $280 | 2021-12-16 | Buy |
Biosynth Carbosynth | BG168444 | Go 6976 | 1mg | $150 | 2021-12-16 | Buy |
Cayman Chemical | 13310 | G? 6976 ≥98% | 500μg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 13310 | G? 6976 ≥98% | 1mg | $92 | 2024-03-01 | Buy |
Cayman Chemical | 13310 | G? 6976 ≥98% | 5mg | $216 | 2024-03-01 | Buy |
ChemScene | CS-0002498 | Go6976 99.34% | 1mg | $200 | 2021-12-16 | Buy |
ChemScene | CS-0002498 | Go6976 99.34% | 5mg | $600 | 2021-12-16 | Buy |
CSNpharm | CSN16571 | Go6976 | 5mg | $124 | 2021-12-16 | Buy |
CSNpharm | CSN16571 | Go6976 | 10mg | $199 | 2021-12-16 | Buy |
Properties
Melting point :>221°C (dec.)
Boiling point :652.3±55.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Acetonitrile (Very Slightly, Heated), DMSO (Slightly), Methanol (Very Slightly)
form :Off-white solid
pka :14.39±0.20(Predicted)
color :White to Off-White
Boiling point :652.3±55.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Acetonitrile (Very Slightly, Heated), DMSO (Slightly), Methanol (Very Slightly)
form :Off-white solid
pka :14.39±0.20(Predicted)
color :White to Off-White
Safety Information
Symbol(GHS): | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
G? 6976 is a nonglycosidic indolocarbazole that inhibits protein kinase C (PKC) with IC50 values of 2.3 and 6.2 nM for PKCα and PKCβ1, respectively. It does not inhibit the activity of PKCδ, PKCε, or PKCζ (IC50s > 3 μM), indicating a preference for the Ca2+-dependent subtypes, PKCα and PKCβ1. G? 6976 also inhibits the checkpoint kinases Chk1/2. It was shown to abrogate DNA damage-induced S- and G2-phase cell cycle arrest, leading to cytotoxicity in p53 mutant tumor cells.Related product price
- 1-(1-METHYL-1H-INDOL-4-YL)METHYLAMINE 97
$186-982.08 - Indole-4-carboxaldehyde
$10-1047 - N-(2-CYANOETHYL)PYRROLE
$15-1142.41
Suppliers and manufacturers
Nantong HI-FUTURE Biology Co., Ltd.
Hubei Jusheng Technology Co.,Ltd.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd