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ChemicalBook >> CAS DataBase List >> CPNQ

CPNQ

CPNQ price.
  • $138 - $1102.4
  • Product name: CPNQ
  • CAS: 115687-05-3
  • MF: C20H17ClN4O3
  • MW: 396.83
  • EINECS:
  • MDL Number:MFCD02039810
  • Synonyms:5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline;B2;Linazolamide intermediate B impurity 2;(4-chlorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone;SIRT2 Inhibitor, B2;Methanone, (4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]-;Sirtuin,Parkinson’s diseases,Huntington’s diseases,Inhibitor,B2,inhibit,B-2;SIRT2-IN-8
9 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 0.5MG
  • 1mg
  • 5mg
  • 10MG
  • 25mg
  • 50MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008461
  • Product descriptionCPNQ 95.00%
  • Packaging0.5MG
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008461
  • Product descriptionCPNQ 95.00%
  • Packaging10MG
  • Price$673.08
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008461
  • Product descriptionCPNQ 95.00%
  • Packaging50MG
  • Price$1102.4
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7209
  • Product descriptionB2
  • Packaging10mg
  • Price$234
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7209
  • Product descriptionB2
  • Packaging50mg
  • Price$959
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC3118
  • Product descriptionCPNQ ≥98% (HPLC), solid
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC3118
  • Product descriptionCPNQ ≥98% (HPLC), solid
  • Packaging25mg
  • Price$719
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB820015
  • Product descriptionB2
  • Packaging1mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number254701
  • Product descriptionB2
  • Packaging10mg
  • Price$403
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0008461 CPNQ 95.00% 0.5MG $138 2021-12-16 Buy
American Custom Chemicals Corporation API0008461 CPNQ 95.00% 10MG $673.08 2021-12-16 Buy
American Custom Chemicals Corporation API0008461 CPNQ 95.00% 50MG $1102.4 2021-12-16 Buy
ApexBio Technology B7209 B2 10mg $234 2021-12-16 Buy
ApexBio Technology B7209 B2 50mg $959 2021-12-16 Buy
Sigma-Aldrich C3118 CPNQ ≥98% (HPLC), solid 5mg $193 2024-03-01 Buy
Sigma-Aldrich C3118 CPNQ ≥98% (HPLC), solid 25mg $719 2021-12-16 Buy
TRC B820015 B2 1mg $200 2021-12-16 Buy
Usbiological 254701 B2 10mg $403 2021-12-16 Buy

Properties

Melting point :174-176°C
Boiling point :645.5±55.0 °C(Predicted)
Density :1.412±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :H2O: insoluble <2mg/mL
pka :2.30±0.29(Predicted)
form :solid
color :brown
Water Solubility :H2O: insoluble <2mg/mL
DMSO: >5mg/mL

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

B2 is a cell permeable inhibitor of SIRT2 (sirtuin 2) (IC50 = 35 μM). B2 promotes inclusion formation in cellular models of both Huntington’s disease and Parkinson’s disease. B2 prevents Huntington-mediated proteasome dysfunction and reduces α-synuclein-mediated toxicity. SIRT2 is known to deacetylate histones.

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