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ChemicalBook >> CAS DataBase List >> CAY10535 Exclusive

CAY10535 Exclusive

CAY10535 Exclusive price.
  • $36 - $1801
  • Product name: CAY10535 Exclusive
  • CAS: 945716-28-9
  • MF: C18H21N3O7S
  • MW: 423.44
  • EINECS:
  • MDL Number:
  • Synonyms:CAY10535 Exclusive;1-tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea;Benzenesulfonamide, N-[[(1,1-dimethylethyl)amino]carbonyl]-2-(3-methoxyphenoxy)-5-nitro-;CAY10535,CAY-10535;N-[[(1,1-dimethylethyl)amino]carbonyl]-2-(3-methoxyphenoxy)-5-nitro-benzenesulfonamide
8 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number9421CW
  • Product description1-Tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea
  • Packaging1mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9421CW
  • Product description1-Tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea
  • Packaging5mg
  • Price$318
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9421CW
  • Product description1-Tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea
  • Packaging10mg
  • Price$488
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9421CW
  • Product description1-Tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea
  • Packaging50mg
  • Price$1801
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010396
  • Product descriptionCAY10535 ≥98%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010396
  • Product descriptionCAY10535 ≥98%
  • Packaging5mg
  • Price$162
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010396
  • Product descriptionCAY10535 ≥98%
  • Packaging10mg
  • Price$286
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010396
  • Product descriptionCAY10535 ≥98%
  • Packaging50mg
  • Price$1498
  • Updated2023-06-20
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9421CW 1-Tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea 1mg $148 2021-12-16 Buy
AK Scientific 9421CW 1-Tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea 5mg $318 2021-12-16 Buy
AK Scientific 9421CW 1-Tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea 10mg $488 2021-12-16 Buy
AK Scientific 9421CW 1-Tert-butyl-3-[2-(3-methoxyphenoxy)-5-nitrophenyl]sulfonylurea 50mg $1801 2021-12-16 Buy
Cayman Chemical 10010396 CAY10535 ≥98% 1mg $36 2024-03-01 Buy
Cayman Chemical 10010396 CAY10535 ≥98% 5mg $162 2024-03-01 Buy
Cayman Chemical 10010396 CAY10535 ≥98% 10mg $286 2024-03-01 Buy
Cayman Chemical 10010396 CAY10535 ≥98% 50mg $1498 2023-06-20 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

TPα and TPβ are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). Although their distinct physiological functions have not been fully elucidated, TPβ is believed to be responsible for vascular endothelial growth factor-induced endothelial cell differentiation and migration whereas TPα appears to be the predominant isoform expressed in platelets. CAY10535 is a TP receptor antagonist that shows ~20-fold selectivity for TPβ (IC50 = 99 nM) relative to TPα (IC50 = 1,970 nM) in the inhibition of U46619-mediated Ca2+ mobilization. This compound exhibits relatively poor activity on platelets (IC50 = 985 nM) when inhibiting U-46619-induced platelet aggregation.1