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ChemicalBook >> CAS DataBase List >> Bexarotene

Bexarotene

Bexarotene price.
  • $31 - $1995
  • Product name: Bexarotene
  • CAS: 153559-49-0
  • MF: C24H28O2
  • MW: 348.48
  • EINECS:
  • MDL Number:MFCD00932428
  • Synonyms:LG 69;RO 26-4455;Targret;Bexarotene(4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentaMethyl-2-naphthalenyl)ethenyl]benzoic acid;Bexarotene, Free;Bexarotenecas;Bexarotene (Targretin Targrexin);Bexarotene(LGD-1069)
40 prices
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  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Chemtos
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
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  • 5G
  • ManufacturerAK Scientific
  • Product numberJ53042
  • Product descriptionBexarotene
  • Packaging500mg
  • Price$348
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63701
  • Product descriptionBexarotene 99+%
  • Packaging100mg
  • Price$136.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63701
  • Product descriptionBexarotene 99+%
  • Packaging300mg
  • Price$319.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0028668
  • Product descriptionBexarotene 95.00%
  • Packaging10MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0028668
  • Product descriptionBexarotene 95.00%
  • Packaging100MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8380
  • Product descriptionBexarotene
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545986
  • Product descriptionBexarotene >98%
  • Packaging10mg
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545986
  • Product descriptionBexarotene >98%
  • Packaging100mg
  • Price$357
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134383
  • Product descriptionBexarotene >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134383
  • Product descriptionBexarotene >99%
  • Packaging250mg
  • Price$606.9
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134383
  • Product descriptionBexarotene >99%
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBB164246
  • Product descriptionBexarotene
  • Packaging10mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18579
  • Product descriptionBexarotene
  • Packaging250mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBB164246
  • Product descriptionBexarotene
  • Packaging100mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18579
  • Product descriptionBexarotene
  • Packaging500mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18579
  • Product descriptionBexarotene
  • Packaging1g
  • Price$180
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J53042 Bexarotene 500mg $348 2021-12-16 Buy
Alfa Aesar J63701 Bexarotene 99+% 100mg $136.65 2024-03-01 Buy
Alfa Aesar J63701 Bexarotene 99+% 300mg $319.65 2024-03-01 Buy
American Custom Chemicals Corporation API0028668 Bexarotene 95.00% 10MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation API0028668 Bexarotene 95.00% 100MG $1732.5 2021-12-16 Buy
ApexBio Technology A8380 Bexarotene 10mg $50 2021-12-16 Buy
Biorbyt Ltd orb545986 Bexarotene >98% 10mg $136 2021-12-16 Buy
Biorbyt Ltd orb545986 Bexarotene >98% 100mg $357 2021-12-16 Buy
Biorbyt Ltd orb134383 Bexarotene >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb134383 Bexarotene >99% 250mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb134383 Bexarotene >99% 1g $1504.5 2021-12-16 Buy
Biosynth Carbosynth BB164246 Bexarotene 10mg $48 2021-12-16 Buy
Biosynth Carbosynth FB18579 Bexarotene 250mg $60 2021-12-16 Buy
Biosynth Carbosynth BB164246 Bexarotene 100mg $97 2021-12-16 Buy
Biosynth Carbosynth FB18579 Bexarotene 500mg $100 2021-12-16 Buy
Biosynth Carbosynth FB18579 Bexarotene 1g $180 2021-12-16 Buy

Properties

Melting point :230-231°C
Boiling point :489.7±44.0 °C(Predicted)
Density :1.042
RTECS :DH6834830
storage temp. :-20°C
solubility :Soluble in DMSO and ethanol
pka :4.08±0.10(Predicted)
form :White powder
color :white to beige
λmax :264nm(MeOH)(lit.)
Merck :14,1194
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
InChIKey :NAVMQTYZDKMPEU-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Bexarotene is a high-affinity ligand for retinoid X receptors (RXRs) (EC50 = 28, 25, and 20 nM for RXRα, β, and γ, respectively). It inhibits cell cycle progression, induces apoptosis, prevents or overcomes multidrug resistance through multidrug resistance protein 1 (MDR1), and blocks angiogenesis and metastasis, making it a promising chemopreventive agent against cancer. Bexarotene also, through RXR activation, stimulates clearance of soluble β-amyloid, reduces plaque area, and reverses deficits related to Alzheimer’s disease in mice.

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