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ChemicalBook >> CAS DataBase List >> BINUCLEINE 2

BINUCLEINE 2

BINUCLEINE 2 price.
  • $36 - $725.46
  • Product name: BINUCLEINE 2
  • CAS: 220088-42-6
  • MF: C13H11ClFN5
  • MW: 291.71
  • EINECS:
  • MDL Number:MFCD00177827
  • Synonyms:Binucleine 2 - CAS 220088-42-6 - Calbiochem;N'-[2-(3-chloro-4-fluorophenyl)-4-cyanopyrazol-3-yl]-N,N-dimethylmethanimidamide;Methanimidamide, N'-[1-(3-chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl]-N,N-dimethyl-
7 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 1mg
  • 2MG
  • 5MG
  • 10mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001278
  • Product descriptionBINUCLEINE 2 95.00%
  • Packaging2MG
  • Price$587.43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001278
  • Product descriptionBINUCLEINE 2 95.00%
  • Packaging5MG
  • Price$725.46
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23367
  • Product descriptionBinucleine 2 ≥98%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23367
  • Product descriptionBinucleine 2 ≥98%
  • Packaging5mg
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23367
  • Product descriptionBinucleine 2 ≥98%
  • Packaging10mg
  • Price$269
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB1186
  • Product descriptionBinucleine 2 ≥97% (HPLC)
  • Packaging2mg
  • Price$104
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB1186
  • Product descriptionBinucleine 2 ≥97% (HPLC)
  • Packaging5mg
  • Price$210
  • Updated2023-01-07
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation KIN0001278 BINUCLEINE 2 95.00% 2MG $587.43 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001278 BINUCLEINE 2 95.00% 5MG $725.46 2021-12-16 Buy
Cayman Chemical 23367 Binucleine 2 ≥98% 1mg $36 2024-03-01 Buy
Cayman Chemical 23367 Binucleine 2 ≥98% 5mg $143 2024-03-01 Buy
Cayman Chemical 23367 Binucleine 2 ≥98% 10mg $269 2024-03-01 Buy
Sigma-Aldrich B1186 Binucleine 2 ≥97% (HPLC) 2mg $104 2024-03-01 Buy
Sigma-Aldrich B1186 Binucleine 2 ≥97% (HPLC) 5mg $210 2023-01-07 Buy

Properties

Boiling point :456.9±55.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5 mg/mL, soluble
form :solid
pka :4.81±0.50(Predicted)
Stability :Moisture Sensitive

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Binucleine 2 is a cell-permeable pyrazolo compound that inhibits cytokinesis function of the ARK-2 pathway. It inhibits Histone H3 phosphorylation on Ser10 in mitotic Drosophila Kc167 cells at 20 μM, while inactive in mammalian systems. Binucleine 2 does neither function as a general kinase inhibitor nor inhibit Cdk-dependent entry into mitosis.