3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide
![3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide price.](/CAS/GIF/860352-01-8.gif)
|
- $25 - $7494.8
- Product name: 3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide
- CAS: 860352-01-8
- MF: C17H19FN4O2S
- MW: 362.42
- EINECS:
- MDL Number:MFCD12406007
- Synonyms:3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide;5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide;AZD 7762;White solid;1-(2-((S)-piperidin-3-ylcarbamoyl)-5-(3-fluorophenyl)thiophen-3-yl)urea;5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide AZD 7762;AZD 7762 5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide;(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide
30 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 1mg
- 2mg
- 10mg
- 50mg
- 250mg
- 10mM(in 1mL DMSO)
- 1unit
- 5MG
- 25MG
- 100mg
- 1G
- ManufacturerAK Scientific
- Product numberSYN5341
- Product descriptionAZD7762
- Packaging100mg
- Price$931
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000916
- Product description(S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00%
- Packaging5MG
- Price$730.54
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000916
- Product description(S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00%
- Packaging25MG
- Price$1127.86
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000916
- Product description(S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00%
- Packaging1G
- Price$7494.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5919
- Product descriptionAZD7762
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5919
- Product descriptionAZD7762
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5919
- Product descriptionAZD7762
- Packaging10mM(in 1mL DMSO)
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5919
- Product descriptionAZD7762
- Packaging25mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5919
- Product descriptionAZD7762
- Packaging100mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60219
- Product descriptionAZD7762 ≥98%
- Packaging10mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1399
- Product descriptionAZD-7762 hydrochloride 99%
- Packaging2mg
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA100917
- Product descriptionAZD 7762
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA100917
- Product descriptionAZD 7762
- Packaging50mg
- Price$472.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11491
- Product descriptionAZD 7762 ≥98%
- Packaging1mg
- Price$25
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11491
- Product descriptionAZD 7762 ≥98%
- Packaging5mg
- Price$56
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11491
- Product descriptionAZD 7762 ≥98%
- Packaging10mg
- Price$100
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5341 | AZD7762 | 100mg | $931 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000916 | (S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00% | 5MG | $730.54 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000916 | (S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00% | 25MG | $1127.86 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000916 | (S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00% | 1G | $7494.8 | 2021-12-16 | Buy |
| ApexBio Technology | A5919 | AZD7762 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A5919 | AZD7762 | 5mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | A5919 | AZD7762 | 10mM(in 1mL DMSO) | $80 | 2021-12-16 | Buy |
| ApexBio Technology | A5919 | AZD7762 | 25mg | $240 | 2021-12-16 | Buy |
| ApexBio Technology | A5919 | AZD7762 | 100mg | $470 | 2021-12-16 | Buy |
| Arctom | CFN60219 | AZD7762 ≥98% | 10mg | $168 | 2021-12-16 | Buy |
| Axon Medchem | Axon1399 | AZD-7762 hydrochloride 99% | 2mg | $66 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA100917 | AZD 7762 | 10mg | $135 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA100917 | AZD 7762 | 50mg | $472.5 | 2021-12-16 | Buy |
| Cayman Chemical | 11491 | AZD 7762 ≥98% | 1mg | $25 | 2024-03-01 | Buy |
| Cayman Chemical | 11491 | AZD 7762 ≥98% | 5mg | $56 | 2024-03-01 | Buy |
| Cayman Chemical | 11491 | AZD 7762 ≥98% | 10mg | $100 | 2024-03-01 | Buy |
Properties
Boiling point :547.6±50.0 °C(Predicted)
Density :1.38
storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
pka :9.06±0.20(Predicted)
color :Yellow or brown
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Density :1.38
storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
pka :9.06±0.20(Predicted)
color :Yellow or brown
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
| Symbol(GHS): |
 
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
Actively proliferating cells experience blocks at certain checkpoints in the cell cycle when DNA damage is detected. These checkpoints allow for DNA damage repair before further cell cycle progression. Targeting signaling pathways to selectively inhibit repair at these checkpoints in tumor cells is of considerable interest to cancer therapeutics. AZD 7762 selectively inhibits the activity of checkpoint kinases (Chk) 1 and Chk2 (IC50s = 5 nM) by competitively and reversibly binding their respective ATP-binding sites (Ki = 3.6 nM for Chk1). AZD 7762 abrogates DNA damage-induced S and G2 checkpoints with an EC50 value of 10 nM and potentiates the efficacy of DNA-damage repair prohibitive agents, gemcitabine and topotecan, both in vitro and in various tumor xenografts by modulating downstream checkpoint pathway proteins.More related product prices
Olaparib 918504-65-1 ABT 263 CHIR-124 SCH900776 MK-1775 Levetiracetam METHOPRENE ACID Fruquintinib|HMPL-013 PomalidomideRelated product price
- Olaparib
$28-2147.1 - 918504-65-1
$29-3960 - ABT 263
$26-2245.7
Suppliers and manufacturers
career henan chemical co
![3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide](https://img.chemicalbook.com/ProductImageEN/2020-3/small/55d307dd-c0da-4943-8d7a-b841f8371d03.jpg)
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei xin bonus chemical co. LTD
CONIER CHEM AND PHARMA LIMITED
Dideu Industries Group Limited
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited
$1.00 /1KG
3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide CAS:860352-01-8
3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide CAS:860352-01-8
