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ChemicalBook >> 1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]-

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]-

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- price.
  • $159 - $633
  • Product name: 1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]-
  • CAS: 831217-43-7
  • MF: C31H32N2O5
  • MW: 512.6
  • EINECS:
  • MDL Number:MFCD18632539
  • Synonyms:4-[1,1′-Biphenyl]-4-yl-3,4-dihydro-6-methyl-2-oxo-5-[(phenylmethoxy)carbonyl]-1(2H)-pyrimidinehexanoic acid;116-9e;1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]-;6-(4-([1,1'-biphenyl]-4-yl)-5-((benzyloxy)carbonyl) -6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)hexanoic acid;116-9e >=98% (HPLC), powder;116 9e,1169e;6-(4-([1,1'-Biphenyl]-4-yl)-5-((benzyloxy)carbonyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)hexanoic acid
2 prices
Selected condition：
Brand
  • Sigma-Aldrich
Package
  • 5mg
  • 25mg
  • ManufacturerSigma-Aldrich
  • Product numberE1036
  • Product description116-9e ≥98% (HPLC), powder
  • Packaging5mg
  • Price$159
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberE1036
  • Product description116-9e ≥98% (HPLC), powder
  • Packaging25mg
  • Price$633
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich E1036 116-9e ≥98% (HPLC), powder 5mg $159 2024-03-01 Buy
Sigma-Aldrich E1036 116-9e ≥98% (HPLC), powder 25mg $633 2024-03-01 Buy

Properties

Boiling point :747.3±60.0 °C(Predicted)
Density :1.205±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :powder
pka :4.76±0.10(Predicted)
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.

Description

116-9e has been used as an inhibitor of heat shock protein 70 (Hsp70) co-chaperone HDJ2 (human Ydj1/DNAJA1) to study the influence of HDJ2 on the regulation of ribonucleotide reductase (RNR) activity in HEK293 cells. It has also been used as an Hsp70 inhibitor to study the effect of Hsp70 chaperone on b5‐ops glycosylation in the side populations (SP) HeLa cells.