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ChemicalBook >> CAS DataBase List >> (-)-LEUKOTRIENE A4 METHYL ESTER

(-)-LEUKOTRIENE A4 METHYL ESTER

(-)-LEUKOTRIENE A4 METHYL ESTER price.
  • $144 - $1967
  • Product name: (-)-LEUKOTRIENE A4 METHYL ESTER
  • CAS: 73466-12-3
  • MF: C21H32O3
  • MW: 332.48
  • EINECS:
  • MDL Number:MFCD00065847
  • Synonyms:(-)-LEUKOTRIENE A4 METHYL ESTER;LEUKOTRIENE A4 METHYL ESTER;(-)-leukotriene A4;LEUKOTRIENE A4-METHYLESTER SOLUTION (100UG/ML HEXANE/1% TRIETHYLAMINE);LTA4 (Leukotriene A4 methyl ester) ;5S-TRANS-5,6-OXIDO-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID, METHYL ESTER;PWXYNAKNLZUYAL-WAQVJNLQSA-N;2-Oxiranebutanoic acid, 3-(1E,3E,5Z,8Z)-1,3,5,8-tetradecatetraen-1-yl-, methyl ester, (2S,3S)-
8 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 25μg
  • 50μg
  • 0.1mg
  • 100μg
  • 0.5mg
  • 500μG
  • 96Tests
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPEP0005576
  • Product descriptionLEUKOTRIENE A4 METHYL ESTER 97.00%
  • Packaging500μG
  • Price$1967
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20010
  • Product descriptionLeukotriene A4 methyl ester ≥97%
  • Packaging500μg
  • Price$1579
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number20010
  • Product descriptionLeukotriene A4 methyl ester ≥97%
  • Packaging100μg
  • Price$519
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20010
  • Product descriptionLeukotriene A4 methyl ester ≥97%
  • Packaging50μg
  • Price$274
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20010
  • Product descriptionLeukotriene A4 methyl ester ≥97%
  • Packaging25μg
  • Price$144
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberL473505
  • Product descriptionLTA4(LeukotrieneA4methylester)
  • Packaging0.1mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberL473505
  • Product descriptionLTA4(LeukotrieneA4methylester)
  • Packaging0.5mg
  • Price$1260
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number366268
  • Product descriptionLeukotriene A4
  • Packaging96Tests
  • Price$938
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation PEP0005576 LEUKOTRIENE A4 METHYL ESTER 97.00% 500μG $1967 2021-12-16 Buy
Cayman Chemical 20010 Leukotriene A4 methyl ester ≥97% 500μg $1579 2023-06-20 Buy
Cayman Chemical 20010 Leukotriene A4 methyl ester ≥97% 100μg $519 2024-03-01 Buy
Cayman Chemical 20010 Leukotriene A4 methyl ester ≥97% 50μg $274 2024-03-01 Buy
Cayman Chemical 20010 Leukotriene A4 methyl ester ≥97% 25μg $144 2024-03-01 Buy
TRC L473505 LTA4(LeukotrieneA4methylester) 0.1mg $290 2021-12-16 Buy
TRC L473505 LTA4(LeukotrieneA4methylester) 0.5mg $1260 2021-12-16 Buy
Usbiological 366268 Leukotriene A4 96Tests $938 2021-12-16 Buy

Properties

storage temp. :−20°C
solubility :Acetone: >50 mg/ml; DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: insoluble and unstable.
form :triethylamine:hexane solution

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H304 May be fatal if swallowed and enters airways Aspiration hazard Category 1 Danger GHS hazard pictograms
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P331 Do NOT induce vomiting.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P391 Collect spillage. Hazardous to the aquatic environment
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Leukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. LTA4 is rapidly metabolized by LTA4 hydrolase or LTC4 synthase to LTB4 or LTC4, respectively. LTA4, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA4 by 15-LO leads to lipoxin biosynthesis. LTA4 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

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