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ChemicalBook >> CAS DataBase List >> 1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide

1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide

1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide price.
  • $32 - $1700
  • Product name: 1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide
  • CAS: 722456-31-7
  • MF: C18H12N6OS
  • MW: 360.39
  • EINECS:
  • MDL Number:MFCD03407188
  • Synonyms:1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide;7-(1,3-Benzoxazol-2-ylsulfanyl)-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine;7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine;VAS 2870;VAS2870;VAS-2870;NOX Inhibitor III, VAS2870 ;2-(3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ylthio)benzo[d]oxazole
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 5
  • 1mg
  • 5mg
  • 10mg
  • 25
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1521CM
  • Product description2-(3-Benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1521CM
  • Product description2-(3-Benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole
  • Packaging10mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1521CM
  • Product description2-(3-Benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole
  • Packaging25mg
  • Price$395
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA564124
  • Product description2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+%
  • Packaging5mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA564124
  • Product description2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA564124
  • Product description2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+%
  • Packaging25mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA564124
  • Product description2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+%
  • Packaging50mg
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA564124
  • Product description2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+%
  • Packaging100mg
  • Price$306
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA564124
  • Product description2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+%
  • Packaging250mg
  • Price$613
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA564124
  • Product description2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+%
  • Packaging1g
  • Price$1532
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0297364
  • Product description1,3-BENZOXAZOL-2-YL-3-BENZYL-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-YL SULFIDE 95.00%
  • Packaging5MG
  • Price$505.97
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545814
  • Product descriptionVAS-2870 >98%
  • Packaging5mg
  • Price$173.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545814
  • Product descriptionVAS-2870 >98%
  • Packaging25mg
  • Price$406.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19205
  • Product descriptionVAS2870 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19205
  • Product descriptionVAS2870 ≥98%
  • Packaging5mg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19205
  • Product descriptionVAS2870 ≥98%
  • Packaging10mg
  • Price$120
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1521CM 2-(3-Benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole 1mg $133 2021-12-16 Buy
AK Scientific 1521CM 2-(3-Benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole 10mg $232 2021-12-16 Buy
AK Scientific 1521CM 2-(3-Benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole 25mg $395 2021-12-16 Buy
Ambeed A564124 2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+% 5mg $38 2021-12-16 Buy
Ambeed A564124 2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+% 10mg $70 2021-12-16 Buy
Ambeed A564124 2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+% 25mg $134 2021-12-16 Buy
Ambeed A564124 2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+% 50mg $235 2021-12-16 Buy
Ambeed A564124 2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+% 100mg $306 2021-12-16 Buy
Ambeed A564124 2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+% 250mg $613 2021-12-16 Buy
Ambeed A564124 2-((3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)benzo[d]oxazole 98+% 1g $1532 2021-12-16 Buy
American Custom Chemicals Corporation CHM0297364 1,3-BENZOXAZOL-2-YL-3-BENZYL-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-YL SULFIDE 95.00% 5MG $505.97 2021-12-16 Buy
Biorbyt Ltd orb545814 VAS-2870 >98% 5mg $173.4 2021-12-16 Buy
Biorbyt Ltd orb545814 VAS-2870 >98% 25mg $406.3 2021-12-16 Buy
Cayman Chemical 19205 VAS2870 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 19205 VAS2870 ≥98% 5mg $78 2024-03-01 Buy
Cayman Chemical 19205 VAS2870 ≥98% 10mg $120 2024-03-01 Buy

Properties

Boiling point :627.0±65.0 °C(Predicted)
Density :1.53±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥5mg/mL
form :Tan solid
pka :0.85±0.30(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

VAS-2870 (722456-31-7) is a NAD(P)H oxidase (Nox) inhibitor. Abolishes PDGF-mediated Nox activation and ROS production (100% at 10 μM). Inhibits PMA-induced oxidative burst in HL-60 cells (IC50=2 μM). VAS-2870 enhances TGF-β-induced apoptosis in liver tumor cells.

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