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ChemicalBook >> CAS DataBase List >> 7,8-Dihydroxycoumarin

7,8-Dihydroxycoumarin

7,8-Dihydroxycoumarin price.
  • $41 - $970
  • Product name: 7,8-Dihydroxycoumarin
  • CAS: 486-35-1
  • MF: C9H6O4
  • MW: 178.14
  • EINECS:207-632-8
  • MDL Number:MFCD00016977
  • Synonyms:7,8-DIHYDROXY-2H-1-BENZOPYRAN-2-ONE;7,8-DIHYDROXY-CHROMEN-2-ONE;7,8-DIHYDROXYCOUMARIN;AKOS 213-37;7,8-dihydroxy-2h-1-benzopyran-2-on ;7,8-dihydroxy-coumari ;DAPHNETIN;7,8-Diydroxycoumarin
36 prices
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Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Ark Pharm
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
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  • ManufacturerAHH
  • Product numberAPI-1622
  • Product descriptionDaphnetin 98%
  • Packaging25g
  • Price$760
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0328
  • Product descriptionDaphnetin
  • Packaging5g
  • Price$831
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0015884
  • Product description7,8-DIHYDROXYCOUMARIN 95.00%
  • Packaging500MG
  • Price$912.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1567
  • Product descriptionDaphnetin
  • Packaging20mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS672702
  • Product descriptionDaphnetin ≥95%
  • Packaging250mg
  • Price$41
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99952
  • Product descriptionDaphnetin ≥98%
  • Packaging20mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS672702
  • Product descriptionDaphnetin ≥95%
  • Packaging5g
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000021181
  • Product descriptionDaphnetin 95+%
  • Packaging50mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000021181
  • Product descriptionDaphnetin 95+%
  • Packaging100mg
  • Price$422
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000021181
  • Product descriptionDaphnetin 95+%
  • Packaging250mg
  • Price$675
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1886
  • Product descriptionDaphnetin
  • Packaging20mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1886
  • Product descriptionDaphnetin
  • Packaging100mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD67369
  • Product description7,8-Dihydroxycoumarin
  • Packaging500mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD67369
  • Product description7,8-Dihydroxycoumarin
  • Packaging1g
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD67369
  • Product description7,8-Dihydroxycoumarin
  • Packaging2g
  • Price$184
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD67369
  • Product description7,8-Dihydroxycoumarin
  • Packaging5G
  • Price$330
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1622 Daphnetin 98% 25g $760 2021-12-16 Buy
AK Scientific V0328 Daphnetin 5g $831 2021-12-16 Buy
American Custom Chemicals Corporation PXT0015884 7,8-DIHYDROXYCOUMARIN 95.00% 500MG $912.45 2021-12-16 Buy
ApexBio Technology N1567 Daphnetin 20mg $100 2021-12-16 Buy
Arctom AS672702 Daphnetin ≥95% 250mg $41 2021-12-16 Buy
Arctom CFN99952 Daphnetin ≥98% 20mg $60 2021-12-16 Buy
Arctom AS672702 Daphnetin ≥95% 5g $375 2021-12-16 Buy
Ark Pharm P000021181 Daphnetin 95+% 50mg $233 2021-12-16 Buy
Ark Pharm P000021181 Daphnetin 95+% 100mg $422 2021-12-16 Buy
Ark Pharm P000021181 Daphnetin 95+% 250mg $675 2021-12-16 Buy
AvaChem 1886 Daphnetin 20mg $49 2021-12-16 Buy
AvaChem 1886 Daphnetin 100mg $149 2021-12-16 Buy
Biosynth Carbosynth FD67369 7,8-Dihydroxycoumarin 500mg $75 2021-12-16 Buy
Biosynth Carbosynth FD67369 7,8-Dihydroxycoumarin 1g $115 2021-12-16 Buy
Biosynth Carbosynth FD67369 7,8-Dihydroxycoumarin 2g $184 2021-12-16 Buy
Biosynth Carbosynth FD67369 7,8-Dihydroxycoumarin 5G $330 2021-12-16 Buy

Properties

Melting point :265-268°C (dec.)
Boiling point :270.35°C (rough estimate)
Density :1.3431 (rough estimate)
refractive index :1.4500 (estimate)
storage temp. :room temp
solubility :soluble in Methanol
form :solid
pka :7.61±0.20(Predicted)
color :White to Light yellow to Light red
biological source :synthetic (organic)
Merck :14,2817
InChI :InChI=1S/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12H
InChIKey :ATEFPOUAMCWAQS-UHFFFAOYSA-N
SMILES :C1(=O)OC2=C(O)C(O)=CC=C2C=C1
LogP :0.884 (est)
CAS DataBase Reference :486-35-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Daphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. Inhibits EGFR kinase (IC50 = 7.67 μM), PKA (IC50 = 9.33 μM), and PKC (IC50 = 25 μM), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as a potent antioxidant and anti-malarial agent.

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