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ChemicalBook >> CAS DataBase List >> 7-Nitroindole-2-carboxylic acid

7-Nitroindole-2-carboxylic acid

7-Nitroindole-2-carboxylic acid price.
  • $7 - $1735.55
  • Product name: 7-Nitroindole-2-carboxylic acid
  • CAS: 6960-45-8
  • MF: C9H6N2O4
  • MW: 206.15
  • EINECS:230-154-6
  • MDL Number:MFCD00044720
  • Synonyms:TIMTEC-BB SBB003487;7-nitro-1h-indole-2-carboxylicaci ;7-NITRO-1H-INDOLE-2-CARBOXYLIC ACID;7-NITROINDOLE-2-CARBOXYLIC ACID;7-Nitroindole-2-carboxylic acid, 90-95%;7-NO2-ICA;2-Carboxy-7-nitro-1H-indole;7-Nitro-1H-indole-2-carboxylic acid 95+%
36 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Atlantic Research Chemicals
  • Cayman Chemical
  • ChemScene
  • Crysdot
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Package
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  • 1gm:
  • 10mM(in 1mL DMSO)
  • ManufacturerAHH
  • Product numberMT-19869
  • Product description7-Nitroindole-2-carboxylicacid 95%
  • Packaging50g
  • Price$828
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ54565
  • Product description7-Nitro-1H-indole-2-carboxylicacid
  • Packaging1g
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB20786
  • Product description7-Nitroindole-2-carboxylic acid, 96%
  • Packaging1g
  • Price$96.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB20786
  • Product description7-Nitroindole-2-carboxylic acid, 96%
  • Packaging5g
  • Price$360.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlichem
  • Product number6960458
  • Product description7-Nitro-1H-indole-2-carboxylicacid
  • Packaging250mg
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number6960458
  • Product description7-Nitro-1H-indole-2-carboxylicacid
  • Packaging500mg
  • Price$1048.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number6960458
  • Product description7-Nitro-1H-indole-2-carboxylicacid
  • Packaging1g
  • Price$1735.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA102798
  • Product descriptionCRT0044876 97%
  • Packaging25mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA102798
  • Product descriptionCRT0044876 97%
  • Packaging50mg
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA102798
  • Product descriptionCRT0044876 97%
  • Packaging100mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA102798
  • Product descriptionCRT0044876 97%
  • Packaging250mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA102798
  • Product descriptionCRT0044876 97%
  • Packaging1g
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA102798
  • Product descriptionCRT0044876 97%
  • Packaging5g
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0028101
  • Product description7-NITROINDOLE-2-CARBOXYLIC ACID 95.00%
  • Packaging1G
  • Price$634.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0028101
  • Product description7-NITROINDOLE-2-CARBOXYLIC ACID 95.00%
  • Packaging2.5G
  • Price$824.49
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0028101
  • Product description7-NITROINDOLE-2-CARBOXYLIC ACID 95.00%
  • Packaging5G
  • Price$960.31
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-19869 7-Nitroindole-2-carboxylicacid 95% 50g $828 2021-12-16 Buy
AK Scientific J54565 7-Nitro-1H-indole-2-carboxylicacid 1g $45 2021-12-16 Buy
Alfa Aesar B20786 7-Nitroindole-2-carboxylic acid, 96% 1g $96.65 2024-03-01 Buy
Alfa Aesar B20786 7-Nitroindole-2-carboxylic acid, 96% 5g $360.65 2024-03-01 Buy
Alichem 6960458 7-Nitro-1H-indole-2-carboxylicacid 250mg $680 2021-12-16 Buy
Alichem 6960458 7-Nitro-1H-indole-2-carboxylicacid 500mg $1048.6 2021-12-16 Buy
Alichem 6960458 7-Nitro-1H-indole-2-carboxylicacid 1g $1735.55 2021-12-16 Buy
Ambeed A102798 CRT0044876 97% 25mg $7 2021-12-16 Buy
Ambeed A102798 CRT0044876 97% 50mg $9 2021-12-16 Buy
Ambeed A102798 CRT0044876 97% 100mg $11 2021-12-16 Buy
Ambeed A102798 CRT0044876 97% 250mg $17 2021-12-16 Buy
Ambeed A102798 CRT0044876 97% 1g $31 2021-12-16 Buy
Ambeed A102798 CRT0044876 97% 5g $104 2021-12-16 Buy
American Custom Chemicals Corporation CHM0028101 7-NITROINDOLE-2-CARBOXYLIC ACID 95.00% 1G $634.25 2021-12-16 Buy
American Custom Chemicals Corporation CHM0028101 7-NITROINDOLE-2-CARBOXYLIC ACID 95.00% 2.5G $824.49 2021-12-16 Buy
American Custom Chemicals Corporation CHM0028101 7-NITROINDOLE-2-CARBOXYLIC ACID 95.00% 5G $960.31 2021-12-16 Buy

Properties

Melting point :260-261 °C
Boiling point :344.99°C (rough estimate)
Density :1.4588 (rough estimate)
refractive index :1.5570 (estimate)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: >20mg/mL
form :Tan solid
pka :4.03±0.30(Predicted)
color :Light yellow to yellow
Water Solubility :Insoluble
CAS DataBase Reference :6960-45-8(CAS DataBase Reference)
EPA Substance Registry System :1H-Indole-2-carboxylic acid, 7-nitro- (6960-45-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Description

Apurinic/apyrimidinic endonuclease-1 (Ape-1) is involved in base excision repair, cleaving the phosphodiester linkage that is 5’ to the abasic site to produce a single strand break. DNA base excision repair pathway inhibitor is a cell-permeable inhibitor of Ape-1 (IC50 = 3-11 μM). Although not toxic to cells by itself at 200 μM, it enhances the cytotoxicity of certain DNA alkylating agents, including temozolomide, when added at this concentration. DNA base excision repair pathway inhibitor has little or no effect on radiation-induced cell survival.

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