4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide

$34 - $750
Product name: 4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide
CAS: 36707-00-3
MF: C13H15N5O6
MW: 337.29
EINECS:
MDL Number:
Synonyms:NSC 177223;4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(β-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide;4-Amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide;API-1;API-1(NSC 177223);Pyrido[2,3-d]pyrimidine-6-carboxamide, 4-amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-;4-Amino-5-oxo-8-pentofuranosyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide;4-amino-8-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide

Price11 Properties Safety Information Description

11 prices

Selected condition：

Brand

Cayman Chemical
CSNpharm
Medical Isotopes, Inc.
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

10
1mg
5mg
10mg
25mg

ManufacturerCayman Chemical
Product number22081
Product descriptionAPI-1 ≥98%
Packaging1mg
Price$34
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number22081
Product descriptionAPI-1 ≥98%
Packaging5mg
Price$152
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number22081
Product descriptionAPI-1 ≥98%
Packaging10mg
Price$270
Updated2024-03-01
Buy

ManufacturerCSNpharm
Product numberCSN22684
Product descriptionAPI-1
Packaging10mg
Price$260
Updated2021-12-16
Buy

ManufacturerCSNpharm
Product numberCSN22684
Product descriptionAPI-1
Packaging25mg
Price$442
Updated2021-12-16
Buy

ManufacturerMedical Isotopes, Inc.
Product number52584
Product descriptionNSC177223
Packaging10mg
Price$750
Updated2021-12-16
Buy

ManufacturerSigma-Aldrich
Product numberSML1342
Product descriptionAPI-1
Packaging5mg
Price$160
Updated2024-03-01
Buy

ManufacturerSigma-Aldrich
Product numberSML1342
Product descriptionAPI-1
Packaging25mg
Price$552
Updated2022-05-15
Buy

ManufacturerTocris
Product number3897
Product descriptionAPI-1 ≥96%(HPLC)
Packaging10
Price$346
Updated2021-12-16
Buy

ManufacturerTRC
Product numberN900270
Product descriptionNSC177223
Packaging5mg
Price$160
Updated2021-12-16
Buy

ManufacturerUsbiological
Product number165663
Product descriptionNSC 177223
Packaging5mg
Price$460
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Cayman Chemical	22081	API-1 ≥98%	1mg	$34	2024-03-01	Buy
Cayman Chemical	22081	API-1 ≥98%	5mg	$152	2024-03-01	Buy
Cayman Chemical	22081	API-1 ≥98%	10mg	$270	2024-03-01	Buy
CSNpharm	CSN22684	API-1	10mg	$260	2021-12-16	Buy
CSNpharm	CSN22684	API-1	25mg	$442	2021-12-16	Buy
Medical Isotopes, Inc.	52584	NSC177223	10mg	$750	2021-12-16	Buy
Sigma-Aldrich	SML1342	API-1	5mg	$160	2024-03-01	Buy
Sigma-Aldrich	SML1342	API-1	25mg	$552	2022-05-15	Buy
Tocris	3897	API-1 ≥96%(HPLC)	10	$346	2021-12-16	Buy
TRC	N900270	NSC177223	5mg	$160	2021-12-16	Buy
Usbiological	165663	NSC 177223	5mg	$460	2021-12-16	Buy

Properties

storage temp. :Store at RT
solubility :DMF: slightly soluble; DMSO: 2 mg/ml
form :powder
color :white to beige

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H301	Toxic if swalloed	Acute toxicity,oral	Category 3	Danger		P264, P270, P301+P310, P321, P330,P405, P501

Precautionary statements:

Description

NSC 177223 is a Akt/protein kinase B inhibitor. It binds to pleckstrin homologous domain of Akt and blocks Akt membrane translocation. Treatment of cancer cells with NSC 177223 results in inhibition of the kinase activities and induction of cell growth arrest and apoptosis selectively in human cancer cells that harbor constitutively activated Akt.