4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid
![4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid price.](/CAS/20180808/GIF/215030-90-3.gif)
|
- $44 - $926
- Product name: 4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid
- CAS: 215030-90-3
- MF: C29H24O2
- MW: 404.5
- EINECS:
- MDL Number:MFCD17215944
- Synonyms:4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoicacid;BMS 493;(E)-4-[2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)naphthalen-2-yl]ethen-1-yl]benzoic acid;4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(phenylethynyl)-2-naphthalenyl]ethenyl]-benzoic acid;BMS204, 493;Benzoic acid, 4-[(1E)-2-[5,6-dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]-;(E)-4-(2-(5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl)vinyl)benzoic acid;BMS493,BMS-493
18 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number4149CR
- Product description4-{(E)-2-[5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoicacid
- Packaging25mg
- Price$572
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4149CR
- Product description4-{(E)-2-[5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoicacid
- Packaging10mg
- Price$313
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7415
- Product descriptionBMS 493
- Packaging5mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17418
- Product descriptionBMS 493 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17418
- Product descriptionBMS 493 ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17418
- Product descriptionBMS 493 ≥98%
- Packaging10mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17418
- Product descriptionBMS 493 ≥98%
- Packaging25mg
- Price$426
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0029097
- Product descriptionBMS 493 98.46%
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0029097
- Product descriptionBMS 493 98.46%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0029097
- Product descriptionBMS 493 98.46%
- Packaging25mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0029097
- Product descriptionBMS 493 98.46%
- Packaging50mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0029097
- Product descriptionBMS 493 98.46%
- Packaging100mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberB6688
- Product descriptionBMS 493 ≥98% (HPLC)
- Packaging5mg
- Price$206
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberB6688
- Product descriptionBMS 493 ≥98% (HPLC)
- Packaging25mg
- Price$812
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number3509
- Product descriptionBMS 493 ≥98%(HPLC)
- Packaging10
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number3509
- Product descriptionBMS 493 ≥98%(HPLC)
- Packaging50
- Price$926
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4149CR | 4-{(E)-2-[5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoicacid | 25mg | $572 | 2021-12-16 | Buy |
| AK Scientific | 4149CR | 4-{(E)-2-[5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoicacid | 10mg | $313 | 2021-12-16 | Buy |
| ApexBio Technology | B7415 | BMS 493 | 5mg | $146 | 2021-12-16 | Buy |
| Cayman Chemical | 17418 | BMS 493 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 17418 | BMS 493 ≥98% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 17418 | BMS 493 ≥98% | 10mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 17418 | BMS 493 ≥98% | 25mg | $426 | 2024-03-01 | Buy |
| ChemScene | CS-0029097 | BMS 493 98.46% | 5mg | $80 | 2021-12-16 | Buy |
| ChemScene | CS-0029097 | BMS 493 98.46% | 10mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-0029097 | BMS 493 98.46% | 25mg | $300 | 2021-12-16 | Buy |
| ChemScene | CS-0029097 | BMS 493 98.46% | 50mg | $550 | 2021-12-16 | Buy |
| ChemScene | CS-0029097 | BMS 493 98.46% | 100mg | $850 | 2021-12-16 | Buy |
| Sigma-Aldrich | B6688 | BMS 493 ≥98% (HPLC) | 5mg | $206 | 2024-03-01 | Buy |
| Sigma-Aldrich | B6688 | BMS 493 ≥98% (HPLC) | 25mg | $812 | 2024-03-01 | Buy |
| Tocris | 3509 | BMS 493 ≥98%(HPLC) | 10 | $220 | 2021-12-16 | Buy |
| Tocris | 3509 | BMS 493 ≥98%(HPLC) | 50 | $926 | 2021-12-16 | Buy |
Properties
Boiling point :605.4±55.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :4.27±0.10(Predicted)
form :powder
color :light yellow to yellow
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :4.27±0.10(Predicted)
form :powder
color :light yellow to yellow
Safety Information
| Symbol(GHS): | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | |||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Nuclear retinoic acid receptors (RARs) are transcriptional regulators with roles in cell proliferation and differentiation. BMS 493 is a pan-RAR inverse agonist that blocks RARα activity with an IC50 value of 114 nM. In all RAR types (RARα, RARβ, and RARγ), BMS493 prevents the recruitment of transcriptional coactivators to RARs while stabilizing corepressor interactions. BMS 493 has been used to elucidate the critical roles of RARs in development and immune response.Related product price
- (-)-Varitriol
$1230 - Ethylamine
$10-1030.84 - ESTETROL
$35-2194.5
