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ChemicalBook >> CAS DataBase List >> (Z)-2-(4-Chlorophenyl)-5-(4-Methoxybenzylidene)-5H-thiazol-4-one

(Z)-2-(4-Chlorophenyl)-5-(4-Methoxybenzylidene)-5H-thiazol-4-one

(Z)-2-(4-Chlorophenyl)-5-(4-Methoxybenzylidene)-5H-thiazol-4-one price.
  • $47 - $1320
  • Product name: (Z)-2-(4-Chlorophenyl)-5-(4-Methoxybenzylidene)-5H-thiazol-4-one
  • CAS: 1272519-89-7
  • MF: C17H12ClNO2S
  • MW: 329.8
  • EINECS:
  • MDL Number:MFCD28127223
  • Synonyms:(Z)-2-(4-Chlorophenyl)-5-(4-Methoxybenzylidene)-5H-thiazol-4-one;(5Z)-2-(4-chlorophenyl)-5-[(4-Methoxyphenyl)Methylene]-4(5H)-thiazolone;4(5H)-Thiazolone, 2-(4-chlorophenyl)-5-[(4-methoxyphenyl)methylene]-, (5Z)-;CAY10649 Exclusive
7 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • ManufacturerAK Scientific
  • Product number8745DG
  • Product description(Z)-2-(4-Chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one
  • Packaging1mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004408
  • Product description(Z)-2-(4-CHLOROPHENYL)-5-(4-METHOXYBENZYLIDENE)-5H-THIAZOL-4-ONE 95.00%
  • Packaging5MG
  • Price$502.05
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10804
  • Product descriptionCAY10649 ≥98%
  • Packaging1mg
  • Price$47
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10804
  • Product descriptionCAY10649 ≥98%
  • Packaging5mg
  • Price$206
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10804
  • Product descriptionCAY10649 ≥98%
  • Packaging10mg
  • Price$360
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC427750
  • Product description(Z)-2-(4-Chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one
  • Packaging1mg
  • Price$165
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC427750
  • Product description(Z)-2-(4-Chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one
  • Packaging10mg
  • Price$1320
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8745DG (Z)-2-(4-Chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one 1mg $149 2021-12-16 Buy
American Custom Chemicals Corporation INB0004408 (Z)-2-(4-CHLOROPHENYL)-5-(4-METHOXYBENZYLIDENE)-5H-THIAZOL-4-ONE 95.00% 5MG $502.05 2021-12-16 Buy
Cayman Chemical 10804 CAY10649 ≥98% 1mg $47 2024-03-01 Buy
Cayman Chemical 10804 CAY10649 ≥98% 5mg $206 2024-03-01 Buy
Cayman Chemical 10804 CAY10649 ≥98% 10mg $360 2024-03-01 Buy
TRC C427750 (Z)-2-(4-Chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one 1mg $165 2021-12-16 Buy
TRC C427750 (Z)-2-(4-Chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one 10mg $1320 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 0.5 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction. CAY10649 is a thiazolinone compound that demonstrates direct inhibition of 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) (IC50 = 0.28 μM) and a soluble fraction of a S100 PMNL cell lysate (IC50 = 0.09 μM) after stimulation with calcium and arachidonic acid.