XL518 suppliers
XL518
- CAS:
- 934660-93-2
- MF:
- C21H21F3IN3O2
- MW:
- 531.31
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Company Type
Properties
- Melting point:
- 165 - 166°C
- Boiling point:
- 565.9±50.0 °C(Predicted)
- Density
- 1.706
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.13±0.20(Predicted)
- color
- Off-White
Safety Information
Use
A potent, selective, orally bioavailable inhibitor of MEK1, a component of the RAS/RAF/MEK/ERK pathway. It inhibits proliferation and stimulates apoptosis in a variety of human tumor cell lines. In preclinical xenograft models, oral administration of XL518 results in sustained inhibition of pERK in tumor tissue, but not brain tissue, leading to tumor growth inhibition and regression at well tolerated doses.
133 supplier list of "XL518"
- Product Name:Cobimetinib
- Products Intro:Purity: 99.98% | Package: 1mg;34USD|2mg;47USD|5mg;77USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
You can find XL518 suppliers,
manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here.
Browse to the tetrahydrofuran product information displayed by the supplier,
as well as the supplier's contact and capability information.