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1-Hydroxybenzotriazole hydrate

1-Hydroxybenzotriazole hydrate ??? ???
?? ??:
123333-53-9
???:
1-Hydroxybenzotriazole hydrate
???(??):
1-HYDROXYBENZOTRIAZOLE MONOHYDRATE;HOBT H2O;HOBT HYDRATE;HOBT.H20;1H-benzo[d][1,2,3]triazol-1-ol hydrate;N-HYDROXYBENZOTRIAZOLE HYDRATE;HOBTM;e hydrate;HOBT MONOHYDRATE;TIMTEC-BB SBB000114
CBNumber:
CB8775919
???:
C6H7N3O2
??? ??:
153.14
MOL ??:
123333-53-9.mol
MSDS ??:
SDS

1-Hydroxybenzotriazole hydrate ??

???
155-158 °C(lit.)
?? ?
248.8°C (rough estimate)
??
1.065 g/cm
???
1.6910 (estimate)
?? ??
Keep in dark place,Inert atmosphere,Room temperature
???
DMF: 100mg/mL, ??
??? ??
??
??? ??
??? ??
??
???? ?????
???
?? ???
BRN
4515
???
???
CAS ??????
123333-53-9(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? F
?? ???? ?? 5-11-R5-R11-44-1
????? 15-16-35-7/9-33-S7/9-S33-S16-60-37-26
????(UN No.) UN 3380 4.1/PG 1
WGK ?? -
F ?????? 4.10-8
?? ?? ?? Highly Flammable
HS ?? 29339980
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H412 ??? ??? ?? ????? ??? ?? ????? ?? - ?? ?? 3 P273, P501
??????:
P210 ?·???·??·????? ????? - ?? ???.
P230 ...?(?) ?? ??? ?????.
P233 ??? ??? ?????. ??? ??? ? ?? ?? ??? ???? ?????.
P280 ????/???/???/?????? ?????.
P370+P380+P375 ?? ? ??? ??? ????, ?? ??? ??? ????? ??? ????? ?? ???.
P501 ...? ??? / ??? ?? ???.

1-Hydroxybenzotriazole hydrate C??? ??, ??, ??

??? ??

White to off-white powder

??

1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare:

?? ??

1-Hydroxybenzotriazole is a coupling reagent used to synthesize amides by the condensation reaction between the activated ester/acid and the amino group of protected amino acids. It is also used as a racemization suppressor during peptide synthesis.

1-Hydroxybenzotriazole hydrate ?? ?? ? ???

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1-Hydroxybenzotriazole hydrate ?? ??

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1-Hydroxybenzotriazole hydrate ?? ??:

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