1-Hydroxybenzotriazole hydrate
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1-Hydroxybenzotriazole hydrate ??
- ???
- 155-158 °C(lit.)
- ?? ?
- 248.8°C (rough estimate)
- ??
- 1.065 g/cm
- ???
- 1.6910 (estimate)
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- Keep in dark place,Inert atmosphere,Room temperature
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- DMF: 100mg/mL, ??
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- BRN
- 4515
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- CAS ??????
- 123333-53-9(CAS DataBase Reference)
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- ?? ? ???? ?? (GHS)
??? ?? | F | ||
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?? ???? ?? | 5-11-R5-R11-44-1 | ||
????? | 15-16-35-7/9-33-S7/9-S33-S16-60-37-26 | ||
????(UN No.) | UN 3380 4.1/PG 1 | ||
WGK ?? | - | ||
F ?????? | 4.10-8 | ||
?? ?? ?? | Highly Flammable | ||
HS ?? | 29339980 |
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?? ?: | Danger | |||||||||||||||||||||
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1-Hydroxybenzotriazole hydrate C??? ??, ??, ??
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White to off-white powder??
1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare:- Poly-γ-glutamic acid methyl ester from a dimer of γ-glutamic acid.
- Oxadiazoles via cyclo condensation of amidoximes with trifluoroacetic anhydride or benzoic acid derivatives.
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1-Hydroxybenzotriazole is a coupling reagent used to synthesize amides by the condensation reaction between the activated ester/acid and the amino group of protected amino acids. It is also used as a racemization suppressor during peptide synthesis.1-Hydroxybenzotriazole hydrate ?? ?? ? ???
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1-Hydroxybenzotriazole hydrate ?? ??
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1-Hydroxybenzotriazole hydrate ?? ??:
????? 4-?????????? 4-??????? ?( ????? D-4-????????? 2-?????????? ????? 4-????? 4'-????????? 1-??????????? ???? ???? ??????
2'-Hydroxy-3-phenylpropiophenone
6-Chloro-1-hydroxibenzotriazol
1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate
Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
BIS(HYDROXYBENZOTRIAZOLYL) CARBONATE