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498-59-9
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DJENKOLIC ACID
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Djenkolic;Djenkolate;jenkolic acid;DJENKOLIC ACID;jengkolic acid;L-DJENKOLIC ACID;Djenkolic Acid >DJENKOLIC ACID, L-;S,S'-Methylenebiscysteine;L-S,S'-METHYLENEDICYSTEINE
CBNumber:
CB7381805
???:
C7H14N2O4S2
??? ??:
254.33
MOL ??:
498-59-9.mol

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325°C (rough estimate)
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515.4±50.0 °C(Predicted)
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D20.5 -65.0° (1.0N HCl); D25 -47.5° (c = 2 in 1.0N HCl)
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1.4799 (rough estimate)
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-65 ° (C=1, 1mol/L HCl)
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2-8°C
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DMSO:0.1(Max Conc. mg/mL);0.39(Max Conc. mM)
Water:25.0(Max Conc. mg/mL);98.3(Max Conc. mM)
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??
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?? ?? (pKa)
pK1:2.200(+1);pK2:8.16(0) (25°C)
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White to off-white
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5g/L(100℃)
Merck
14,3387
CAS ??????
498-59-9(CAS DataBase Reference)
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  • ?? ? ???? ?? (GHS)
HS ?? 2930909899
????(GHS): GHS hazard pictograms
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H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
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P261 ??·?·??·???·??·...·????? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.

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ChEBI: A dithioacetal consisting of two molecules of L-cysteine joined via their sulfanyl groups to methylene.

Purification Methods

Crystallise djenkolic acid from a large volume of water (solubility is 0.5g%). [du Vigneaud & Patterson J Biol Chem 114 533 1936, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2682, 2687 1961, Beilstein 4 III 1591.] The N,N’-dibenzoyl derivative crystallises with 1H2O from aqueous EtOH with m 87.5-89o [Beilstein 9 III 1171.]

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