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Dimethyl acetylsuccinate

Dimethyl acetylsuccinate ??? ???
?? ??:
10420-33-4
???:
Dimethyl acetylsuccinate
???(??):
DMAS;UNII:LOE57K9I2C;Dimethyl acetylsucci;Dimethyl acetylsuccite;DIMETHYL ACETYLSUCCINATE;Doimethyl Acetylsuccinate;Dimethyl Acetylsuccinate >DiMethyl acetylsuccinate (DMAS);ACETYLSUCCINIC ACID DIMETHYL ESTER;acetyl-butanedioicacidimethylester
CBNumber:
CB0421498
???:
C8H12O5
??? ??:
188.18
MOL ??:
10420-33-4.mol
MSDS ??:
SDS

Dimethyl acetylsuccinate ??

???
33 °C (lit.)
?? ?
129-134 °C/12 mmHg (lit.)
??
1.16 g/mL at 25 °C (lit.)
???
19.6Pa at 25℃
???
>230 °F
?? ??
Sealed in dry,Room Temperature
???
30g/l OECD ?? ????? 105
?? ?? (pKa)
10.53±0.59(Predicted)
??? ??
solid
??
White or Colorless to Almost white or Almost colorless
????
0.72-11.1%(V)
???
water: soluble 56.2g/L at20°C
LogP
0.69 at 35℃ and pH7
CAS ??????
10420-33-4(CAS DataBase Reference)
EPA
Butanedioic acid, acetyl-, dimethyl ester (10420-33-4)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
WGK ?? 1
TSCA Yes
HS ?? 2918.30.7000
???? ?? KE-00112
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
0 0

Dimethyl acetylsuccinate C??? ??, ??, ??

??

Dimethyl Acetylsuccinate was used in preparation of β-carbolines via diastereo- and enantioselective Bronsted acid catalyzed N-acyliminium cyclization cascades of tryptamines and keto acids/esters.

?? ??

Dimethyl acetylsuccinate undergoes sulfuric acid catalyzed Pechmann condensation with the corresponding resorcinol derivative to give 7-hydroxycoumarins.

Dimethyl acetylsuccinate ?? ?? ? ???

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Dimethyl acetylsuccinate ?? ??

???( 188)?? ??
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Dimethyl acetylsuccinate ?? ??:

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