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L 2-401

化學構(gòu)造式
883050-24-6
CAS番號.
883050-24-6
化學名:
別名:
英語名:
L 2-401
英語別名:
CS-563;L 2-401;CCG 50014;CCG50014;CCG 50014;CCG-50014 >=98% (HPLC);CCG-50014, 10 mM in DMSO;4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione;4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione;1,2,4-Thiadiazolidine-3,5-dione, 4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-;Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,inhibit,CCG50014,Inhibitor
CBNumber:
CB82657938
化學式:
C16H13FN2O2S
分子量:
316.35
MOL File:
883050-24-6.mol

L 2-401 物理性質(zhì)

比重(密度) :
1.398±0.06 g/cm3 (20 ºC 760 Torr)
貯蔵溫度 :
2-8°C
溶解性:
DMSO：可溶5mg/mL、透明（加溫）
外見 :
粉
色:
白からベージュ

安全性情報

WGK Germany  3

L 2-401 価格 もっと(4)

メーカー 製品番號 製品説明 CAS番號 包裝 価格 更新時間 購入
富士フイルム和光純薬株式會社(wako) W01TOC4567
CCG 50014 		883050-24-6 10mg ￥65000 2023-06-01 購入
富士フイルム和光純薬株式會社(wako) W01TOC4567
CCG 50014 		883050-24-6 50mg ￥277000 2023-06-01 購入
Sigma-Aldrich Japan SML0908 ≥98% (HPLC)
CCG-50014 ≥98% (HPLC)		 883050-24-6 5mg ￥25100 2024-03-01 購入
Sigma-Aldrich Japan SML0908 ≥98% (HPLC)
CCG-50014 ≥98% (HPLC)		 883050-24-6 25mg ￥64100 2024-03-01 購入

L 2-401 化學特性,用途語,生産方法

説明

CCG-50014 is an inhibitor of regulator of G protein signaling 4 (RGS4) (IC50 = 30 nM) and is > 20-fold selective for RGS4 over other RGS proteins. RGS proteins bind to the Gα subunits of activated heterotrimeric G proteins and accelerate the rate of GTP hydrolysis, acting as GTPase-activating proteins. CCG-50014 irreversibly binds and destabilizes RGS4 with no effect on Gα0, while blocking GTPase activity and Gα0-dependent translocation of RGS4 to the membrane.

L 2-401 上流と下流の製品情報

原材料

準備製品

L 2-401 生産企業(yè)

Global( 82)Suppliers
名前 電話番號 電子メール 國籍 製品カタログ 優(yōu)位度
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32965 60
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30236 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826
 market@aladdin-e.com China 25003 65
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
 China 4573 55

  スペクトルデータ(1HNMR)

  • 883050-24-6
  • 4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione
  • CCG 50014
  • L 2-401
  • 1,2,4-Thiadiazolidine-3,5-dione, 4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-
  • 4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione
  • CCG50014;CCG 50014
  • CS-563
  • CCG-50014 >=98% (HPLC)
  • Regulators of G-protein Signaling,Regulator of G-protein Signaling,RGS Protein,CCG-50014,inhibit,CCG50014,Inhibitor
  • CCG-50014, 10 mM in DMSO
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