タザロテン 化學(xué)特性,用途語,生産方法
外観
白色～黃色～緑色粉末～結(jié)晶
効能
抗ニキビ薬, 乾癬治療薬, 角質(zhì)溶解薬, レチノイン酸受容體(RAR)作動薬
化學(xué)的特性
White Solid
使用
Tazarotene is a prescription topical retinoid sold as a cream or gel. This medication is approved for treatment of psoriasis, acne, and sun damaged skin (photodamage). It is commonly sold in two concentrations: 0.05% and 0.1%. In addition to tretinoin, wh
適応癥
Like other retinoids, tazarotene (Tazorac) acts by binding
to RARs and altering gene expression. Tazarotene
appears to be particularly selective for the retinoid receptors
RAR-β and RAR-γ, but the clinical significance
of this observation is unknown.
定義
ChEBI: The ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin.
臨床応用
In the United States, tazarotene has been approved
for topical treatment of psoriasis (involving up to 20%
body surface area) and mild to moderate facial acne.
Application site burning, stinging, and desquamation are
common side effects, especially with acne. Tazarotene is
contraindicated in women who are pregnant.
副作用
Tazorac is a category X drug and must be avoided in pregnancy. This drug
can be irritating and should be avoided in patients with sensitive skin or
seborrheic dermatitis.
タザロテン 上流と下流の製品情報
原材料
準(zhǔn)備製品