Sevelamer carbonate
Sevelamer carbonate 物理性質(zhì)
- 貯蔵溫度 :
- Room Temperature, under inert atmosphere
- 溶解性:
- <4.74mg/mL in DMSO
- 外見 :
- 個體
- 色:
- ホワイト～ペールベージュ
- InChI:
- InChI=1S/C3H5ClO.C3H7N.CH2O3/c4-1-3-2-5-3;1-2-3-4;2-1(3)4/h3H,1-2H2;2H,1,3-4H2;(H2,2,3,4)
- InChIKey:
- PADGNZFOVSZIKZ-UHFFFAOYSA-N
- SMILES:
- C(O)(O)=O.C(C1OC1)Cl.C(=C)CN
安全性情報
- リスクと安全性に関する聲明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
|
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
區(qū)分 |
注意喚起語 |
シンボル |
P コード |
| H412 |
長期的影響により水生生物に有害 |
水生環(huán)境有害性、慢性毒性 |
3 |
|
|
P273, P501 |
|
| 注意書き |
| P273 |
環(huán)境への放出を避けること。 |
| P501 |
內(nèi)容物/容器を．．．に廃棄すること。 |
|
Sevelamer carbonate 価格
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時間 |
購入 |
Sevelamer carbonate 化學(xué)特性,用途語,生産方法
説明
Sevelamer carbonate (SC) is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. SC has been found to have the same safety and efficacy profile as Sevelamer HCl in HD patients.
Sevelamer carbonate(Renvela) is a nonaluminum, non-calcium-basedphosphorus binder that traps phosphorus in the bowel through ion exchange and hydrogen binding. This drug replaced sevelamer hydrochloride(Renagel) and has an advantage of not generating an acid load, as its precursor, sevelamer hydrochloride, did. It also has the advantage of lowering LDL cholesterol due to gut binding of bile acids.
使用
Sevelamer Carbonate, a non-?absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-?based phosphate binders.
Mode of action
The active substance in Sevelamer carbonate Winthrop, sevelamer carbonate, is a phosphate binder. When taken with meals, it attaches in the gut to phosphate from the food, thereby preventing the phosphate from being absorbed into the body and helping to reduce phosphate levels in the blood.
Sevelamer carbonate 上流と下流の製品情報
原材料
準(zhǔn)備製品
Sevelamer carbonate 生産企業(yè)
Global( 205)Suppliers
845273-93-0()キーワード:
- 845273-93-0
- 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
- Sevelamer carbonate
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- 2-Propen-1-aminepolymerwith
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- SIM862 Sevelamer Carbonate-----25gm
- Sevelamer Carbonate, Technical Grade
- 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate ISO 9001：2015 REACH
- Sevelam carbonate
- SEVELEMER CARBONATE