ヒト遺伝子組換ポリペプチド-10 化學(xué)特性,用途語,生産方法
外観
10mMTris-HCL(pH7.5),1mMDTT,2M NaCLを含む1mg/mLの溶液を0.2μmろ過滅菌後凍結(jié)乾燥
定義
本品は、大腸菌 E.coli によって産生させた単鎖の遺伝子組換ヒトペプチドである。出発遺伝子は、酸性線維芽細(xì)胞成長因子-1のコードを持つヒト細(xì)胞から直接単離されたものである。酸性線維芽細(xì)胞成長因子-1は、ジスルフィド結(jié)合と糖鎖付加の両方またはいずれか一方を含む最大で155個(gè)のアミノ酸からなり、固有のアミノ酸配列を持つ。
化粧品の成分用途
皮膚コンディショニング剤
一般的な説明
FGF-2 (fibroblast growth factor 2) is a basic heparin binding growth factor. It is ubiquitously expressed and belongs to the FGF family. It is also referred to as BFGF (basic fibroblast growth factor). The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.
Biochem/physiol Actions
FGF-2 (fibroblast growth factor 2, also referred to as BFGF (basic fibroblast growth factor)) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. It is present in the preimplantation embryos and is important for proper development. It is also responsible for angiogenesis. FGF-2 plays a crucial role in adipogenesis and development of adipose tissues. It is associated with tumor growth and metastasis.
ヒト遺伝子組換ポリペプチド-10 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品