抗ラミンA(C末端)抗體 ウサギ宿主抗體 化學(xué)特性,用途語,生産方法
使用
Mouse monoclonal clone 4C11 anti-Lamin A/C antibody is used to tag lamins A and/or C for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques such as immunoblotting, immunoprecipitation, and immunofluorescence. It is used as a probe to determine the presence and roles of lamins A and/or C in nuclear envelope structure and function. This antibody may be used in several immunochemical techniques including immunoblotting (~72/63 kDa), immunoprecipitation and immunofluorescence.
一般的な説明
Lamin is a structural protein of the nuclear lamina. Lamin A is a type A lamin encoded by the LMNA gene. Lamin A contains 664 amino acids and is expressed in most somatic cells. It contains α-helical rod domain to enable assembly into filaments, a nuclear localization sequence, and a carboxy-terminal CAAX box isoprenylation sequence for nuclear membrane targeting.
Biochem/physiol Actions
Lamin A cut into a 47kDa fragment that facilitates chromatin condensation and nuclear degradation during cell death
抗ラミンA(C末端)抗體 ウサギ宿主抗體 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品