4F-ベンゾイル-TN14003 価格

メーカー	製品番號(hào)	製品説明	CAS番號(hào)	包裝	価格	更新時(shí)間	購(gòu)入

4F-ベンゾイル-TN14003 化學(xué)特性,用途語(yǔ),生産方法

酵素阻害剤

This orally bioavailable, disulfide cross-linked, polyphemusin-II-derived peptide antagonist (sequence shown above, with Nal = naphthylamine, Cit = citrulline, D-Lys = D-Lysine, and Cys = half-cystine), also known as 4-Fbenzoyl-TN14003 and BL-8040, targets CXC Chemokine Receptor-4 (CXCR4), a G-protein-coupled receptor that is directly involved in tumor progression, tumor angiogenesis, metastasis, and cancer cell survival. Primary Mode of Inhibitory Action: CXCR4 is over-expressed in more than 70% of human cancers and its expression often correlates with disease severity. BKT140 exhibits high affinity (Ki = 0.8nM) and a low rate of dissociation from its receptor. BKT140 prevents the binding of stromal derived factor-1 (SDF-1 or CXCL12) to CXCR4 activation, resulting in decreased tumor cell proliferation and migration. In addition, inhibition of CXCR4 may mobilize hematopoietic cell egress from the bone marrow and into blood. BKT140 significantly and preferentially stimulates multiple myeloma apoptotic cell death, as indicated by induced morphological changes, phosphatidylserine externalization, decreased mitochondrial membrane potential, caspase-3 activation, sub-G1 cell-cycle arrest, as well as DNA double-stranded breaks.

4F-ベンゾイル-TN14003 上流と下流の製品情報(bào)

原材料

準(zhǔn)備製品

4F-ベンゾイル-TN14003 生産企業(yè)

名前	電話番號(hào)	電子メール	國(guó)籍	製品カタログ	優(yōu)位度
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33025	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Shanghai Longyu Biotechnology Co., Ltd.	+8619521488211	info@longyupharma.com	China	2558	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29809	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3512	58
Nanjing TGpeptide	+86-13347807150 +86-13347807150	support@tgpeptide.com	China	3279	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2943	58

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• 664334-36-5
• BL-8040
• BKT140
• BKT140CXCR4 antagonist
• BKT140 (BL-8040)
• BKT140 4-fluorobenzoyl
• MOTIXAFORTIDE;BL-8040;TF14016
• 4F-Benzoyl-TN14003
• BL-8040; TF14016; 4F-BENZOYL-TN14003
• TF14016
• BKT140, >99%
• BKT140,BL-8040,TF14016,4F-Benzoyl-TN14003, >99%
• L-Argininamide, N2-(4-fluorobenzoyl)-L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-D-lysyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide
• Motixafortide
• Motixafortide(TFA)
• (3S,6S,9S,12R,17R,20S,23S,26S,29R,34AS)-N-((S)-1-amino-5-guanidino-1-oxopentan-2-yl)-26,29-bis(4-aminobutyl)-17-((S)-2-((S)-2-((S)-2-(4-fluorobenzamido)-5-guanidinopentanamido)-5-guanidinopentanamido)-3-(naphthalen-2-yl)propanamido)-6-(3-guanidinopropyl)-3,20-bis(4-hydroxybenzyl)-1,4,7,10,18,21,24,27,30-nonaoxo-9,23-bis(3-ureidopropyl)dotriacontahydropyrrolo[2,1-p][1,2,5,8,11,14,17,20,23,26,29]dithianonaazacyclodotriacontine-12-carboxamide
• Motixafortide(BKT140)
• {4-Fluorobenzoyl}-Arg-Arg-{2-Naph-Ala}-Cys-Tyr-{Cit}-Lys-{d-Lys}-Pro-Tyr-Arg-{Cit}-Cys-Arg-NH2 (Disulfide bridge: Cys4-Cys13)
• (3S,6S,9S,12R,17R,20S,23S,26S,29R,34aS)-N-((S)-1-Amino-5-guanidino-1-oxopentan-2-yl)-26,29-bis(4-aminobutyl)-17-((S)-2-((S)-2-((S)-2-(4-fluorobenzamido)-5-guanidinopentanamido)-5-guanidinopentanamido)-3-(naphthalen-2-yl)propanamido)-6-(3-guanidinopropyl)-3,20-bis(4-hydroxybenzyl)-1,4,7,10,18,21,24,27,30-nonaoxo-9,23-bis(3-ureidopropyl)triacontahydro-1H,16H-pyrrolo[2,1-p][1,2]dithia[5,8,11,14,17,20,23,26,29]nonaazacyclodotriacontine-12-carboxamide
• (2S)-N-[(1S)-1-{[(1S)-1-{[(3S,6S,9S,12R,17R,20S,23S,26S,29R,34aS)-26-(4-アミノブチル)-12-{[(1S)-4-カルバムイミドアミド-1-カルバモイルブチル]カルバモイル}-6-(3-カルバムイミドアミドプロピル)-9,23,29-トリス[3-(カルバモイルアミノ)プロピル]-3,20-ビス[(4-ヒドロキシフェニル)メチル]-1,4,7,10,18,21,24,27,30-ノナオキソ-ドトリアコンタヒドロピロロ[2,1-p]1,2-ジチア-5,8,11,14,17,20,23,26,29-ノナアザシクロドトリアコンタン-17-イル]カルバモイル}-2-(ナフタレン-2-イル)エチル]カルバモイル}-4-カルバムイミドアミドブチル]-5-カルバムイミドアミド-2-[(4-フルオロフェニル)ホルムアミド]ペンタンアミド
• Nα-(4-フルオロベンゾイル)-L-Arg-L-Arg-L-βNal-L-Cys(1)-L-Tyr-L-Cit-L-Lys-D-Cit-L-Pro-L-Tyr-L-Arg-L-Cit-L-Cys(1)-L-Arg-NH2
• 4-フルオロベンゾイル-L-Arg-L-Arg-L-βNal-L-Cys(1)-L-Tyr-L-Cit-L-Lys-D-Lys-L-Pro-L-Tyr-L-Arg-L-Cit-L-Cys(1)-L-Arg-NH2
• Nα-(4-フルオロベンゾイル)-L-Arg-L-Arg-L-βNal-L-Cys(1)-L-Tyr-L-Cit-L-Lys-D-Lys-L-Pro-L-Tyr-L-Arg-L-Cit-L-Cys(1)-L-Arg-NH2
• 4F-ベンゾイル-TN14003
• 4F-ベンゾイル-TN-14003
• (2S)-N-[(1S)-1-{[(1S)-1-{[(3S,6S,9S,12R,17R,20S,23S,26S,29R,34aS)-26,29-ビス(4-アミノブチル)-12-{[(1S)-4-カルバムイミドアミド-1-カルバモイルブチル]カルバモイル}-6-(3-カルバムイミドアミドプロピル)-9,23-ビス[3-(カルバモイルアミノ)プロピル]-3,20-ビス[(4-ヒドロキシフェニル)メチル]-1,4,7,10,18,21,24,27,30-ノナオキソ-ドトリアコンタヒドロピロロ[2,1-p]1,2-ジチア-5,8,11,14,17,20,23,26,29-ノナアザシクロドトリアコンタン-17-イル]カルバモイル}-2-(ナフタレン-2-イル)エチル]カルバモイル}-4-カルバムイミドアミドブチル]-5-カルバムイミドアミド-2-[(4-フルオロフェニル)ホルムアミド]ペンタンアミド
• Nα-(4-フルオロベンゾイル)-L-Arg-L-Arg-3-(2-ナフチル)-L-Ala-L-Cys(1)-L-Tyr-L-Cit-L-Lys-D-Lys-L-Pro-L-Tyr-L-Arg-L-Cit-L-Cys(1)-Arg-NH2