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ChemicalBook >> CAS DataBase List >>Brodalumab

Brodalumab

CAS No.
1174395-19-7
Chemical Name:
Brodalumab
Synonyms
Brodalumab;Brodalumab (anti-IL17RA);LP 0160|||KHK-4827|||AMG-827;Research Grade Brodalumab(DHJ38901)
CBNumber:
CB94845996
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD01864808
MOL File:
Mol file
Last updated:2024-11-19 23:02:33

Brodalumab Properties

storage temp. Store at -20°C
form Liquid
color Colorless to light yellow
FDA UNII 6ZA31Y954Z
ATC code L04AC12

Pharmacokinetic data

Excreted unchanged in urine Minimal
Volume of distribution 7.24 Litres
Biological half-life 10.9 days

Brodalumab Chemical Properties,Uses,Production

Uses

Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque psoriasis.

Clinical Use

Human monoclonal immunoglobulin IgG2 antibody:

Treatment of moderate to severe plaque psoriasis

Drug interactions

Potentially hazardous interactions with other drugs
Avoid with live vaccines.

Metabolism

Brodalumab is expected to be degraded into small peptides and amino acids via catabolic pathways in a manner similar to endogenous IgG. Brodalumab is expected to be mainly eliminated via catabolism and hepatic impairment is not expected to influence clearance.

Brodalumab Preparation Products And Raw materials

Raw materials

Preparation Products

Brodalumab Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Guangzhou Hongyuan Chemical Co.,Ltd 15817493340 981810490@qq.com China 1566 58
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062 422450190@qq.com China 10436 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58
Biolab Reagents 027-65279366 18108604862 products@biolabreagent.com China 9818 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 13720134139 13720134139 orders@jknbiochem.com China 5821 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 market@aladdin-e.com China 48461 58
Changsha Fuzhen Biotechnology Co.,LTD 18670069958 18670069958 3062105966@qq.com China 3262 58

View Lastest Price from Brodalumab manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Brodalumab pictures 2024-11-19 Brodalumab
1174395-19-7
US $155.00-582.00 / mg 98.4% (SEC-HPLC) 10g TargetMol Chemicals Inc.
  • Brodalumab pictures
  • Brodalumab
    1174395-19-7
  • US $155.00-582.00 / mg
  • 98.4% (SEC-HPLC)
  • TargetMol Chemicals Inc.
Brodalumab Research Grade Brodalumab(DHJ38901) Brodalumab (anti-IL17RA) LP 0160|||KHK-4827|||AMG-827 1174395-19-7