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ChemicalBook >> CAS DataBase List >>2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine

2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine

CAS No.
701224-63-7
Chemical Name:
2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine
Synonyms
GLX481304;2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine;1,3,5-Triazine-2,4-diamine, N2-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)-1-piperazinyl]methyl]-
CBNumber:
CB94524471
Molecular Formula:
C23H29N7O
Molecular Weight:
419.52
MDL Number:
MOL File:
701224-63-7.mol
Last updated:2025-04-28 21:36:36

2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine Properties

Boiling point 666.5±65.0 °C(Predicted)
Density 1.250±0.06 g/cm3(Predicted)
form Solid
pka 5.90±0.10(Predicted)
color White to off-white

2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine Chemical Properties,Uses,Production

Uses

GLX481304 is a specific inhibitor of Nox-2 and -4, with IC50s of 1.25 μM. GLX481304 suppresses ROS production in isolated mouse cardiomyocytes and improves cardiomyocyte contractility. GLX481304 can be used for research of ischemic injury to the heart[1].

References

[1] Szekeres FLM, et al. A small molecule inhibitor of Nox2 and Nox4 improves contractile function after ischemia-reperfusion in the mouse heart. Sci Rep. 2021 Jun 7;11(1):11970. DOI:10.1038/s41598-021-91575-8

2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine Preparation Products And Raw materials

Raw materials

Preparation Products

2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19905 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19965 58

View Lastest Price from 2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine manufacturers

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GLX481304 pictures 2025-04-28 GLX481304
701224-63-7
 US $0.00-0.00 / mg 10g TargetMol Chemicals Inc.
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2-N-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)piperazin-1-yl]methyl]-1,3,5-triazine-2,4-diamine 1,3,5-Triazine-2,4-diamine, N2-(3,4-dimethylphenyl)-6-[[4-(3-methoxyphenyl)-1-piperazinyl]methyl]- GLX481304 701224-63-7