ChemicalBook >> CAS DataBase List >>PVM/MA
PVM/MA
- CAS No.
- 1644545-52-7
- Chemical Name:
- PVM/MA
- Synonyms
- AG881;E7386;AG081;HS-01;PVM/MA;AG-881;E-7386;dsadas;s-22611;FF10101
- CBNumber:
- CB91403717
- Molecular Formula:
- C14H13ClF6N6
- Molecular Weight:
- 414.74
- MDL Number:
- MFCD31630835
- MOL File:
- 1644545-52-7.mol
Last updated:2025-04-29 17:45:46
| Boiling point | 467.5±55.0 °C(Predicted) |
|---|---|
| Density | 1.491±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml |
| form | A crystalline solid |
| pka | 1.49±0.41(Predicted) |
| color | Light yellow to light brown |
| FDA UNII | 789Q85GA8P |
| NCI Drug Dictionary | vorasidenib |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
PVM/MA price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28462 | Vorasidenib | 1644545-52-7 | 1mg | $110 | 2024-03-01 | Buy |
| Cayman Chemical | 28462 | Vorasidenib | 1644545-52-7 | 10mg | $757 | 2024-03-01 | Buy |
| Cayman Chemical | 28462 | Vorasidenib | 1644545-52-7 | 5mg | $433 | 2024-03-01 | Buy |
| ChemScene | CS-8033 | Vorasidenib 99.87% | 1644545-52-7 | 5mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-8033 | Vorasidenib 99.87% | 1644545-52-7 | 10mg | $250 | 2021-12-16 | Buy |
PVM/MA Chemical Properties,Uses,Production
Uses
PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.
Synthesis
Maleic anhydride (MA) was added to a solvent mixture of cyclohexane and ethyl acetate in a polymerizer equipped with an agitator, a reflux condenser, and an inner temperature-controlling device. The polymerizer was purged of air and filled with nitrogen. The solution was heated to 70 °C, and then an initiator solution (lauroyl peroxide dissolved in ethyl acetate) and Methyl vinyl ether (MVE) were added to the polymerizer in a dropwise manner. A slurry was obtained, which was filtered and dried under a vacuum to obtain a white powdery copolymer.
IC 50
IDH1; IDH2
PVM/MA Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 115)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3074 | 58 |
| Wuhan Nutra Biotechnology Co.,Ltd | +8617786394783 | nutrabiotech@outlook.com | China | 300 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
Related articles
- The brief introduction of PVM/MA
- The copolymer of MVE and maleic anhydride (MA) is most widely used.
- Mar 14，2024
View Lastest Price from PVM/MA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-12 | PVM/MA
00-00-0
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2025-05-01 | AKR1C3-IN-9 | US $38.00-118.00 / mg | 99.41% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-04-29 | Vorasidenib
1644545-52-7
|
US $48.00-122.00 / mg | 99.57% | 10g | TargetMol Chemicals Inc. |
-
- PVM/MA
00-00-0
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- AKR1C3-IN-9
- US $38.00-118.00 / mg
- 99.41%
- TargetMol Chemicals Inc.
-
- Vorasidenib
1644545-52-7
- US $48.00-122.00 / mg
- 99.57%
- TargetMol Chemicals Inc.
1644545-52-7(PVM/MA)Related Search:
PF06291874
Vorasidenib
PVM/MA
S-N-NITROSO-2-METHYLPIPERIDINE
PCB138/160
FLEABUSTERSRXPOWDER
15-HYDROPEROXYEICOSATETRAENOICACID
CALCIUM(C10-C16)ALKYLBENZENESULPHONATE
(5Z,8Z,11Z,14Z)-15-Hydroperoxy-5,8,11,14-icosatetraenoic acid
(5Z,8Z,11Z,14Z)-15-Hydroperoxyicosa-5,8,11,14-tetraenoic acid
15-HPETE
AG881
AG-881
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E7386
E-7386
s-22611
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AG081
FF10101
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2,2'-(propane-2,2- diylbis(sulfanediyl))bis(ethan-1-ol)
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HS-01
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2-[1-(2-Hydroxy-ethylsulfanyl)-1-methyl-ethylsulfanyl]-ethanol
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IMB-XH1
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(+)-Quassin
high quality 3-aminophenylacetylene HCL
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4-hydrazineylnicotinamide
inhibit,AG 881,Vorasidenib,AG881,Inhibitor,Isocitrate Dehydrogenase (IDH)
SRD5A1-IN-1
AKR1C3-IN-9
ARUK2001607
TLC Plates,Silca Gel 60 F254 Aluminium Plating
2-(1-ethoxyvinyl)-4,4,5,5-tetraethyl-1,3,2-dioxaborolane
(S)-1-amino-1-(5-bromo-2-fluorophenyl)ethan-1-ol
N-Difluoromethyltriazolyl-4-carboxamide
N-Trifluoromethyltriazolyl-4-carboxamide
4-Cyano-1-(perfluoroethoxy)pyridin-1-ium bis((trifluoromethyl)sulfonyl)amide
Sodium 2-azido-2,2-difluoroacetate
(1-(2,2,3,3-Tetrafluoropropyl)-1H-1,2,3-triazol-4-yl)methanaminium chloride
1-Difluoroethyltriazolyl-4-methylamine hydrochloride