ChemicalBook >> CAS DataBase List >>(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
- CAS No.
- 201856-53-3
- Chemical Name:
- (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
- Synonyms
- Paclitaxel side chains;SIDE CHAINS OF PACLITAXEL--1;(3R,4S)-1-Benzoyl-3-(2-Ethoxye;1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone;(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone;(3R,4S)-1-benzoyl-3-(1-ethoxyethoxy)-4-phenylazetidin-2-one;(3R,4S)-3-(1-ethoxyethoxy)-4-phenyl-N-benzoyl-2-azetidinone;(3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXYL)-4-PHENYL-2-AZETIDINONE;2-Azetidinone,1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-, (3R,4S)-;(3R,4S)-1-Benzoyl-3-(1-Ethoxyethoxy)-4-Phenyl-2-AzetidinoneCasNo.
- CBNumber:
- CB8854814
- Molecular Formula:
- C20H21NO4
- Molecular Weight:
- 339.39
- MDL Number:
- MFCD09752076
- MOL File:
- 201856-53-3.mol
Last updated:2023-05-04 15:13:49
| Boiling point | 464.8±55.0 °C(Predicted) |
|---|---|
| Density | 1.22 |
| storage temp. | 2-8°C |
| pka | -4.83±0.60(Predicted) |
| CAS DataBase Reference | 201856-53-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FB148182 | (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone | 201856-53-3 | 50mg | $63 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB148182 | (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone | 201856-53-3 | 100mg | $110 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB148182 | (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone | 201856-53-3 | 250mg | $220 | 2021-12-16 | Buy |
| AK Scientific | Q749 | (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone | 201856-53-3 | 250mg | $347 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB148182 | (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone | 201856-53-3 | 500mg | $380 | 2021-12-16 | Buy |
(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Chemical Properties,Uses,Production
Uses
(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone is an investigational intermediate chemical for Paclitaxel and Docetaxel.
Synthesis
To a solution of 2.35 g (10 mmol) of cis-3-(1-ethoxyethoxy)-4-phenylazetidin-2-one in 40 mL of THF at -78° C, was added 6.1 mL (10.07 mmol) of a 1.65M solution of n-butyllithium in hexane. The mixture was stirred for 10 min at -78° C and a solution of 1.42 g (10.1 mmol) of benzoyl chloride in 10 mL of THF was added. The mixture was stirred at -78° C for 1 h diluted with 70 mL of saturated aqueous sodium bicarbonate and extracted with three 50 mL portions of ethyl acetate. The combined ethyl acetate extracts were dried over sodium sulfate and concentrated to give 3.45 g of oil. Chromatography of the oil on silica gel eluted with ethyl acetate/hexane gave 3.22 g (95%) of (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone as a colorless oil.
Synthesis of (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone from Benzoyl chloride and (3R,4S)-3-(1-Ethoxyethoxy)-4-phenyl-2-azetidinone
(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 77)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21639 | 55 |
| Shanghai finete Pharmaceutical Co., Ltd. | +86-18221039705 | CHINA | 139 | 55 | |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32820 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29815 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15361 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
View Lastest Price from (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-10-31 | (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
201856-53-3
|
US $0.00 / Kg/Bag | 2Kg/Bag | 99% up, High Density | 20 tons | Sinoway Industrial co., ltd. | |
 |
2020-11-18 | (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
201856-53-3
|
US $63.00 / KG | 1KG | 99 | 1000KG | Longyan Tianhua Biological Technology Co., Ltd | |
 |
2020-02-14 | (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
201856-53-3
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
201856-53-3
- US $0.00 / Kg/Bag
- 99% up, High Density
- Sinoway Industrial co., ltd.
-
- (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
201856-53-3
- US $63.00 / KG
- 99
- Longyan Tianhua Biological Technology Co., Ltd
-
- (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
201856-53-3
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
201856-53-3((3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone)Related Search:
1of4
(3R,4S)-1-Benzoyl-3-(1-Ethoxyethoxy)-4-Phenyl-2-AzetidinoneCasNo.
(3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXYL)-4-PHENYL-2-AZETIDINONE
(3R,4S)-3-(1-ethoxyethoxy)-4-phenyl-N-benzoyl-2-azetidinone
(3R,4S)-1-Benzoyl-3-(2-Ethoxye
DOCETAXEL SIDE CHAIN / (3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXY)-4-PHENYL-2-PHENYL-AZETIDIONE
(3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXYL) -4-PHENYL-2-AZETIDINONE 97%
SIDE CHAINS OF PACLITAXEL--1
(3R,4S)-1-benzoyl-3-(1-ethoxyethoxy)-4-phenylazetidin-2-one
(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
Paclitaxel side chains
2-Azetidinone,1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-, (3R,4S)-
Paclitaxel Side Chain (Azelidinone) 1-Benzoyl-3-(1-Ethoxyethoxy)-4-Phenyl-2-Azetidinone
(3R, 4S) -1-Benzoyl-3- (1-ethoxyethoxy) -4-phenyl-2-azacyclobutanone
201856-53-3
Intermediates