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ChemicalBook >> CAS DataBase List >>AG473

AG473

CAS No.
133550-22-8
Chemical Name:
AG473
Synonyms
AG473;EGFR-IN-16;Benzenepropanenitrile, α-[(3,4-dihydroxyphenyl)methylene]-β-oxo-, (αE)-
CBNumber:
CB85854617
Molecular Formula:
C16H11NO3
Molecular Weight:
265.27
MDL Number:
MFCD04745301
MOL File:
133550-22-8.mol
Last updated:2025-04-18 09:52:57

AG473 Properties

Boiling point 497.4±45.0 °C(Predicted)
Density 1.350±0.06 g/cm3(Predicted)
pka 8.78±0.10(Predicted)

AG473 Chemical Properties,Uses,Production

Uses

EGFR-IN-16 (compound 3) is a potent EGFR inhibitor with pIC50 of 4.85 and 4.74 for EGFR and HER-2, respectively[1].

IC 50

EGFR: 4.85 (pIC50); HER2: 4.74 (pIC50)

References

[1] Kamath S, et al. Receptor-guided alignment-based comparative 3D-QSAR studies of benzylidene malonitrile tyrphostins as EGFR and HER-2 kinase inhibitors. J Med Chem. 2003;46(22):4657-4668. DOI:10.1021/jm030065n

AG473 Preparation Products And Raw materials

Raw materials

Preparation Products

AG473 Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		support@targetmol.com United States 38663 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19905 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 6439 55
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10523 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24863 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2672 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 233051 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12000 58

View Lastest Price from AG473 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
EGFR-IN-16 pictures 2024-11-19 EGFR-IN-16
133550-22-8
 US $195.00-370.00 / mg 10g TargetMol Chemicals Inc.
  • EGFR-IN-16 pictures
  • EGFR-IN-16
    133550-22-8
  • US $195.00-370.00 / mg
  • TargetMol Chemicals Inc.
AG473 Benzenepropanenitrile, α-[(3,4-dihydroxyphenyl)methylene]-β-oxo-, (αE)- EGFR-IN-16 133550-22-8