成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook >> CAS DataBase List >>ABT 702 Dihydrochloride

ABT 702 Dihydrochloride

CAS No.
1188890-28-9
Chemical Name:
ABT 702 Dihydrochloride
Synonyms
CS-2726;ABT702 hcl;ABT-702;ABT702;ABT 702;ABT-702 dihydrochloride, 10 mM in DMSO;5-(3-Bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2,3-d]pyrimidin-4-amine dihydrochloride;Pyrido[2,3-d]pyrimidin-4-amine, 5-(3-bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]-, hydrochloride (1:2);ABT702 dihydrochloride,ABT702,ADK,Inhibitor,inhibit,ABT 702,ABT-702,Adenosine Kinase,ABT 702 dihydrochloride
CBNumber:
CB83354238
Molecular Formula:
C22H19N6OBr.2HCl
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-05-18 11:31:02

ABT 702 Dihydrochloride Properties

storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility insoluble in H2O; ≥107.2 mg/mL in DMSO; ≥9.84 mg/mL in EtOH with gentle warming and ultrasonic
form solid
color Orange

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

ABT 702 Dihydrochloride price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A112435 ABT702Dihydrochloride 1188890-28-9 10mg $280 2021-12-16 Buy
AK Scientific 9463CW AdenosineKinaseInhibitor 1188890-28-9 100mg $460 2021-12-16 Buy
ChemScene CS-0025018 ABT-702dihydrochloride 96.36% 1188890-28-9 5mg $150 2021-12-16 Buy
ChemScene CS-0025018 ABT-702dihydrochloride 96.36% 1188890-28-9 50mg $750 2021-12-16 Buy
ChemScene CS-0025018 ABT-702dihydrochloride 96.36% 1188890-28-9 100mg $1100 2021-12-16 Buy
Product number Packaging Price Buy
A112435 10mg $280 Buy
9463CW 100mg $460 Buy
CS-0025018 5mg $150 Buy
CS-0025018 50mg $750 Buy
CS-0025018 100mg $1100 Buy

ABT 702 Dihydrochloride Chemical Properties,Uses,Production

Biological Activity

adenosine (ado) is an endogenous homeostatic inhibitory neuromodulator that reduces cellular excitability at sites of tissue injury and inflammation. inhibition of adenosine kinase (ak), the primary metabolic enzyme for ado, selectively increases ado concentrations at sites of tissue trauma and enhances the analgesic and antiinflammatory actions of ado. abt 702 is a novel, potent nonnucleoside ak inhibitor.

in vitro

abt 702 was active both in inhibiting ak (ic50 ) 1.7 nm) and ado phosphorylation in the intact cells (ic50 ) 50 nm). abt 702 was also highly selective for ak inhibition as compared to other sites of ado action including ada, ado receptors, and ado transport sites [1].

in vivo

abt 702 had dose-dependent antinociceptive and antiinflammatory actions in a variety of animal models of nociceptive, inflammatory, and neuropathic pain. abt 702 is the first of a novel class of potent, selective, non-nucleoside, orally active ak inhibitors that have potent antinociceptive effects in animal models [1].

IC 50

1.7 nm for adenosine kinase

References

[1] lee ch, jiang m, cowart m, gfesser g, perner r, kim kh, gu yg, williams m, jarvis mf, kowaluk ea, stewart ao, bhagwat ss. discovery of 4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido[2,3-d]pyrimidine, an orally active, non-nucleoside adenosine kinase inhibitor.. j med chem. 2001 jun 21;44(13):2133-8.

ABT 702 Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32965 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2922 55
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4727 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4571 55

ABT 702 Dihydrochloride Spectrum

ABT702 hcl CS-2726 ABT-702;ABT702;ABT 702 5-(3-Bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2,3-d]pyrimidin-4-amine dihydrochloride ABT702 dihydrochloride,ABT702,ADK,Inhibitor,inhibit,ABT 702,ABT-702,Adenosine Kinase,ABT 702 dihydrochloride ABT-702 dihydrochloride, 10 mM in DMSO Pyrido[2,3-d]pyrimidin-4-amine, 5-(3-bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]-, hydrochloride (1:2) 1188890-28-9