ChemicalBook >> CAS DataBase List >>CYCLO(-HIS-PRO)
CYCLO(-HIS-PRO)
- CAS No.
- 53109-32-3
- Chemical Name:
- CYCLO(-HIS-PRO)
- Synonyms
- Cyclo(HP);Cyclo(Pro-His);CYCLO(-HIS-PRO);HIS-PRO, CYCLIC;Cyclo-Pro-His-HO;CYCLO(HIS-PRO), >99%;Vitamin B6 Impurity 93;Cyclo(histidyl-proline);Protirelin EP Impurity E;Cyclo(L-histidyl-L-proline)
- CBNumber:
- CB8279260
- Molecular Formula:
- C11H14N4O2
- Molecular Weight:
- 234.25
- MDL Number:
- MFCD00133207
- MOL File:
- 53109-32-3.mol
Last updated:2025-02-10 22:08:48
| Melting point | 162-164 °C |
|---|---|
| Boiling point | 659.3±48.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 1 mg/ml |
| form | A neat oil |
| pka | 12.73±0.40(Predicted) |
| color | Light yellow to yellow |
| FDA UNII | Q10817UXVT |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
CYCLO(-HIS-PRO) price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FC49257 | Cyclo(L-His-L-Pro) | 53109-32-3 | 25mg | $83.5 | 2021-12-16 | Buy |
| ChemScene | CS-6320 | Cyclo(his-pro) | 53109-32-3 | 5mg | $90 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC49257 | Cyclo(L-His-L-Pro) | 53109-32-3 | 50mg | $140.5 | 2021-12-16 | Buy |
| ChemScene | CS-6320 | Cyclo(his-pro) | 53109-32-3 | 10mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC49257 | Cyclo(L-His-L-Pro) | 53109-32-3 | 100mg | $225 | 2021-12-16 | Buy |
CYCLO(-HIS-PRO) Chemical Properties,Uses,Production
Uses
Cyclo(L-histidyl-L-proline) is used in the pharmaceutical composition comprising cyclo(His-Pro) for preventing or treating obesity.
Definition
ChEBI: Cyclo(L-His-L-Pro) is a homodetic cyclic peptide resulting from the formal condensation of both the amino and acid groups of L-histidine with the acid and amino groups of L-proline. It is a metabolite of thyrotropin-releasing hormone (TRH). It has a role as a human blood serum metabolite, a dopamine uptake inhibitor and an anti-inflammatory agent. It is a homodetic cyclic peptide, a dipeptide, a pyrrolopyrazine and a member of imidazoles. It is functionally related to a L-histidine and a L-proline.
CYCLO(-HIS-PRO) Preparation Products And Raw materials
Raw materials
Preparation Products
CYCLO(-HIS-PRO) Suppliers
Global( 92)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Moxin Chemicals | +8617320513646 | mike@molcoo.com | China | 9773 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19819 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 3939 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30231 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
View Lastest Price from CYCLO(-HIS-PRO) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-03-31 | Protirelin EP Impurity E
53109-32-3
|
US $0.00-0.00 / mg | 10mg | 98%+ | 100000 | Moxin Chemicals | |
 |
2024-11-19 | Cyclo(his-pro)
53109-32-3
|
US $31.00-122.00 / mg | 99.87% | 10g | TargetMol Chemicals Inc. |
-
- Protirelin EP Impurity E
53109-32-3
- US $0.00-0.00 / mg
- 98%+
- Moxin Chemicals
-
- Cyclo(his-pro)
53109-32-3
- US $31.00-122.00 / mg
- 99.87%
- TargetMol Chemicals Inc.
53109-32-3(CYCLO(-HIS-PRO))Related Search:
2,5-Dimethylpiperazine
1-Methylpiperazin-2-one
DL-2-AMINOPROPIONIC ANHYDRIDE
CYCLO(-ALA-ALA)
CIS-2,5-DIMETHYLPIPERAZINE
CYCLO-(D-PRO-L-ALA-D-ALA-L-2-AMINO-8-OXO-9,10-EPOXYDECANOIC ACID),Cyclo[D-Pro-L-Ala-D-Ala-2-(6-oxo-6-oxiranylhexyl)-L-Gly-]
Cyclo(L-Pro-L-Val-)
CYCLO(-GLY-HIS)
1-ETHYL-2-METHYL-PIPERAZINE
CYCLO(-GLY-PRO)
1of4
(3S,6S)-3-(3H-imidazol-4-ylmethyl)-1,4-diazabicyclo[4.4.0]decane-2,5-dione
Histidylproline diketopiperazine
histidylproline dioxopiperazine
Cyclo-Pro-His-HO
HIS-PRO, CYCLIC
CYCLO(-HIS-PRO)
Cyclo(histidyl-proline)
CYCLO(HISTIDYL-PROLINE); HISTIDYLPROLINE DIKETOPIPERAZINE
CYCLO(HIS-PRO), >99%
Cyclo(his-pro),Cyclo(histidyl-proline),Histidylproline diketopiperazine, >99%
Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-imidazol-4-ylmethyl)-, (3S,8aS)-
Protirelin EP Impurity E
3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Cyclo(L-histidyl-L-proline)
(3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Cyclo(his-pro) (Cyclo(histidyl-proline))
Endogenous Metabolite,active,orally,inflammatory,inhibit,tyreotropin-releasing,stress,NF-κB,Cyclo(his-pro),hormone,Nuclear factor-κB,cyclic,Cyclo(hispro),Histidylproline diketopiperazine,Cyclo(histidyl-proline),dipeptide,Cyclo(his pro),Inhibitor,Nuclear factor-kappaB,responses
Cyclo(HP)
(3S,8aS)-3-[(4-Imidazolyl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Cyclo(Pro-His)
Vitamin B6 Impurity 93
Nebivolol Impurity 10 Monomer
53109-32-3
Peptides
Releasing Factors
TRH
Biochemicals and Reagents
Amino Acids and Peptides
BioChemical