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ChemicalBook >> CAS DataBase List >>CYCLO(-HIS-PRO)

CYCLO(-HIS-PRO)

CAS No.
53109-32-3
Chemical Name:
CYCLO(-HIS-PRO)
Synonyms
Cyclo(HP);Cyclo(Pro-His);CYCLO(-HIS-PRO);HIS-PRO, CYCLIC;Cyclo-Pro-His-HO;CYCLO(HIS-PRO), >99%;Vitamin B6 Impurity 93;Cyclo(histidyl-proline);Protirelin EP Impurity E;Cyclo(L-histidyl-L-proline)
CBNumber:
CB8279260
Molecular Formula:
C11H14N4O2
Molecular Weight:
234.25
MDL Number:
MFCD00133207
MOL File:
53109-32-3.mol
Last updated:2025-02-10 22:08:48

CYCLO(-HIS-PRO) Properties

Melting point 162-164 °C
Boiling point 659.3±48.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 1 mg/ml
form A neat oil
pka 12.73±0.40(Predicted)
color Light yellow to yellow
FDA UNII Q10817UXVT
UNSPSC Code 12352209
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3

CYCLO(-HIS-PRO) price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FC49257 Cyclo(L-His-L-Pro) 53109-32-3 25mg $83.5 2021-12-16 Buy
ChemScene CS-6320 Cyclo(his-pro) 53109-32-3 5mg $90 2021-12-16 Buy
Biosynth Carbosynth FC49257 Cyclo(L-His-L-Pro) 53109-32-3 50mg $140.5 2021-12-16 Buy
ChemScene CS-6320 Cyclo(his-pro) 53109-32-3 10mg $150 2021-12-16 Buy
Biosynth Carbosynth FC49257 Cyclo(L-His-L-Pro) 53109-32-3 100mg $225 2021-12-16 Buy
Product number Packaging Price Buy
FC49257 25mg $83.5 Buy
CS-6320 5mg $90 Buy
FC49257 50mg $140.5 Buy
CS-6320 10mg $150 Buy
FC49257 100mg $225 Buy

CYCLO(-HIS-PRO) Chemical Properties,Uses,Production

Uses

Cyclo(L-histidyl-L-proline) is used in the pharmaceutical composition comprising cyclo(His-Pro) for preventing or treating obesity.

Definition

ChEBI: Cyclo(L-His-L-Pro) is a homodetic cyclic peptide resulting from the formal condensation of both the amino and acid groups of L-histidine with the acid and amino groups of L-proline. It is a metabolite of thyrotropin-releasing hormone (TRH). It has a role as a human blood serum metabolite, a dopamine uptake inhibitor and an anti-inflammatory agent. It is a homodetic cyclic peptide, a dipeptide, a pyrrolopyrazine and a member of imidazoles. It is functionally related to a L-histidine and a L-proline.

CYCLO(-HIS-PRO) Preparation Products And Raw materials

Raw materials

Preparation Products

CYCLO(-HIS-PRO) Suppliers

Global( 92)Suppliers
Supplier Tel Email Country ProdList Advantage
Moxin Chemicals
+8617320513646 mike@molcoo.com China 9773 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-+86-371-66670886 info@dakenam.com China 19819 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 3939 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30231 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24727 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38630 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58

View Lastest Price from CYCLO(-HIS-PRO) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Protirelin EP Impurity E pictures 2025-03-31 Protirelin EP Impurity E
53109-32-3
US $0.00-0.00 / mg 10mg 98%+ 100000 Moxin Chemicals
Cyclo(his-pro) pictures 2024-11-19 Cyclo(his-pro)
53109-32-3
US $31.00-122.00 / mg 99.87% 10g TargetMol Chemicals Inc.
  • Cyclo(his-pro) pictures
  • Cyclo(his-pro)
    53109-32-3
  • US $31.00-122.00 / mg
  • 99.87%
  • TargetMol Chemicals Inc.
(3S,6S)-3-(3H-imidazol-4-ylmethyl)-1,4-diazabicyclo[4.4.0]decane-2,5-dione Histidylproline diketopiperazine histidylproline dioxopiperazine Cyclo-Pro-His-HO HIS-PRO, CYCLIC CYCLO(-HIS-PRO) Cyclo(histidyl-proline) CYCLO(HISTIDYL-PROLINE); HISTIDYLPROLINE DIKETOPIPERAZINE CYCLO(HIS-PRO), >99% Cyclo(his-pro),Cyclo(histidyl-proline),Histidylproline diketopiperazine, >99% Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-imidazol-4-ylmethyl)-, (3S,8aS)- Protirelin EP Impurity E 3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(L-histidyl-L-proline) (3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(his-pro) (Cyclo(histidyl-proline)) Endogenous Metabolite,active,orally,inflammatory,inhibit,tyreotropin-releasing,stress,NF-κB,Cyclo(his-pro),hormone,Nuclear factor-κB,cyclic,Cyclo(hispro),Histidylproline diketopiperazine,Cyclo(histidyl-proline),dipeptide,Cyclo(his pro),Inhibitor,Nuclear factor-kappaB,responses Cyclo(HP) (3S,8aS)-3-[(4-Imidazolyl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(Pro-His) Vitamin B6 Impurity 93 Nebivolol Impurity 10 Monomer 53109-32-3 Peptides Releasing Factors TRH Biochemicals and Reagents Amino Acids and Peptides BioChemical